Zopiclone (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

• Confusion—more common in older adults
• Clumsiness or unsteadiness—more common in older adults
• Daytime anxiety and/or restlessness
• Difficulty with coordination—more common in older adults
• Mood or mental changes

• Drowsiness (severe)
• Shortness of breath
• Difficult or labored breathing
• Tightness in chest
• Wheezing
• Skin rash
• Aggressiveness
• Behavior changes

• Memory problems—more common in older patients
• Behavior or mental changes

Get emergency help immediately if any of the following symptoms of overdose occur:

• Clumsiness
• Unsteadiness
• Mental or mood changes
• Drowsiness (severe)
• Unusual tiredness or weakness
• Sluggishness
• Reduced physical activity
• Unusual sleepiness
• Loss of consciousness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Dizziness
• Dryness of mouth
• Heartburn
• Impaired vision
• Increased appetite
• Indigestion
• Loss of appetite—more common in older adults
• Stomach upset
• Difficulty speaking
• Constipation
• Decreased muscle tone
• Weight loss

• Agitation—more common in older adults
• Chills
• Fast, irregular, or pounding heartbeat—more common in older adults
• Feeling of heaviness of arms and legs
• Increase in the amount of saliva—more common in older adults
• Increased sweating—more common in older adults
• Tingling, burning or prickly sensation
• Trembling and shaking of fingers, hands, arms, feet, or legs—more common in older adults
• Vomiting—more common in older adults

After you stop using this medicine, it may still produce some side effects that need attention. During this period of time, check with your doctor immediately if you notice the following side effects:

• Abdominal or stomach cramps or pain
• Nausea
• Vomiting
• More difficulty in sleeping than before treatment
• Muscle cramps or discomfort
• Anxiety
• Nervousness
• Irritability
• Restlessness
• Increased sweating
• Tremors
• Seizures

Zopiclone may cause you to have a coated tongue, bad breath, or a bitter taste. These effects are to be expected when you are taking this medicine.

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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