Zolmitriptan (Oral Route)

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Before Using

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

There is no specific information comparing use of zolmitriptan in children or teenagers with use in other age groups.

Geriatric

There is no specific information comparing use of zolmitriptan in patients older than 65 years of age with use in younger adults.

Pregnancy

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Almotriptan
• Cisapride
• Dihydroergotamine
• Eletriptan
• Ergoloid Mesylates
• Ergonovine
• Ergotamine
• Frovatriptan
• Isocarboxazid
• Levomethadyl
• Linezolid
• Mesoridazine
• Methylergonovine
• Methysergide
• Naratriptan
• Phenelzine
• Pimozide
• Procarbazine
• Rizatriptan
• Sumatriptan
• Terfenadine
• Thioridazine
• Tranylcypromine
• Ziprasidone

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Acecainide
• Ajmaline
• Amiodarone
• Amisulpride
• Amitriptyline
• Amoxapine
• Aprindine
• Azimilide
• Bretylium
• Chloroquine
• Citalopram
• Clarithromycin
• Clovoxamine
• Desipramine
• Desvenlafaxine
• Dibenzepin
• Disopyramide
• Dofetilide
• Dolasetron
• Doxepin
• Droperidol
• Duloxetine
• Erythromycin
• Escitalopram
• Femoxetine
• Flecainide
• Fluconazole
• Fluoxetine
• Fluvoxamine
• Foscarnet
• Gemifloxacin
• Halofantrine
• Haloperidol
• Hydroquinidine
• Ibutilide
• Imipramine
• Isradipine
• Lidoflazine
• Lorcainide
• Mefloquine
• Milnacipran
• Nefazodone
• Nortriptyline
• Octreotide
• Paroxetine
• Pentamidine
• Pirmenol
• Prajmaline
• Probucol
• Procainamide
• Prochlorperazine
• Propafenone
• Protriptyline
• Quetiapine
• Quinidine
• Reboxetine
• Risperidone
• Sematilide
• Sertindole
• Sertraline
• Sibutramine
• Sotalol
• Spiramycin
• St John's Wort
• Sultopride
• Tapentadol
• Tedisamil
• Trifluoperazine
• Trimipramine
• Vasopressin
• Venlafaxine
• Vilazodone
• Zimeldine
• Zotepine

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Cimetidine

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Angina (chest pain) or
• Fast or irregular heartbeat or
• Heart or blood vessel disease or
• High blood pressure or
• Kidney disease or
• Liver disease or
• Stroke (history of)—The chance of side effects may be increased. Heart or blood vessel disease and high blood pressure sometimes do not cause any symptoms, so some people do not know that they have these problems. Before deciding whether you should use zolmitriptan, your doctor may need to do some tests to make sure that you do not have any of these conditions.

• Phenylketonuria (PKU)—The oral disintegrating tablets may contain aspartame, which can make your condition worse

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