Zonisamide (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Discouragement
• Feeling sad or empty
• Irritability
• Lack of appetite
• Loss of interest or pleasure
• Mood or mental changes
• Shakiness or unsteady walking
• Tiredness
• Trouble with concentrating
• Trouble with sleeping

• Agitation
• Bruising
• Delusions
• Hallucinations
• Large, flat blue or purplish patches on the skin
• Rash

Get emergency help immediately if any of the following symptoms of overdose occur:

• Difficult or labored breathing
• Faintness
• Loss of consciousness
• Slow or irregular heartbeat

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Abdominal or stomach pain
• Anxiety
• Difficulty with memory
• Dizziness
• Double vision
• Headache
• Loss of appetite
• Nausea
• Restlessness
• Sleepiness
• Sleeplessness
• Unusual drowsiness
• Unusual tiredness or weakness

• Aching muscles or joints
• Acid or sour stomach
• Bad, unusual, or unpleasant taste in the mouth
• Belching
• Change in taste
• Chills
• Constipation
• Diarrhea
• Difficulty with speaking
• Difficulty with thinking
• Dry mouth
• Fever
• General ill feeling
• Headache
• Heartburn
• Indigestion
• Mental slowness
• Nervousness
• Runny or stuffy nose
• Sneezing
• Tingling, burning, or prickly feelings on the skin
• Uncontrolled, back and forth, or rolling eye movements
• Weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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