Pegfilgrastim (Subcutaneous Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common
  • Fever
  • Granulocytopenia, including chills; cough; fever; sore throat; ulcers; sores, or white spots in the mouth
Rare
  • Bluish lips or skin
  • Pain, left upper abdomen or shoulder
  • Shortness of breath; tightness in the chest; troubled breathing; or wheezing
Incidence not known
  • Bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
  • Cough
  • Difficulty swallowing
  • Dizziness
  • Fast heartbeat
  • Flushing or redness of the skin
  • Hives or welts
  • Itching, puffiness, or swelling of the eyelids or around the eyes, face, lips, or tongue
  • Large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • Skin rash
  • Sores on the skin
  • Unusual tiredness or weakness
  • Unusually warm skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Abdominal pain
  • Acid or sour stomach; belching; heartburn; indigestion; or stomach discomfort, upset, or pain
  • Bone pain
  • Change in sense of taste
  • Constipation
  • Diarrhea
  • Fatigue
  • Hair loss or thinning of hair
  • Headache
  • Joint pain
  • Lack or loss of strength
  • Loss of appetite or weight loss
  • Mucositis, including cracked lips; diarrhea; difficulty in swallowing; or sores, ulcers, or white spots on the lips, tongue, or inside the mouth
  • Muscle soreness
  • Nausea
  • Swelling of the hands, ankles, feet, or lower legs
  • Swelling or inflammation of the mouth
  • Trouble sleeping
  • Vomiting
  • Weakness, generalized
Incidence not known
  • Body produces substance that can bind to drug making it less effective or cause side effects

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Precautions

DR601479

Portions of this document last updated:

Nov. 1, 2009

Source: Drug Information provided by: Micromedex

Copyright © 2009 Thomson Healthcare Inc. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.


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