Mayo Clinic Health Manager
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In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of rosiglitazone in the pediatric population. Safety and efficacy have not been established .
Geriatric
Appropriate studies performed to date have not demonstrated geriatrics-specific problems that would limit the usefulness of rosiglitazone in the elderly .
Pregnancy
| Pregnancy Category | Explanation | |
|---|---|---|
| All Trimesters | C | Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women. |
Breastfeeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Drug Interactions
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Bitter Melon
- Fenugreek
- Gemfibrozil
- Glucomannan
- Guar Gum
- Psyllium
- Rifampin
- St John's Wort
- Trimethoprim
Other Interactions
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
- Diabetic ketoacidosis (ketones in the blood) or
- Lactic acidosis (lactic acid in the blood) or
- Metabolic acidosis (extra acids in the blood) or
- Type 1 diabetes—Patients with any of these conditions should not use this medicine .
- Diabetic macular edema (swelling of the back of the eye) or
- Edema or
- Jaundice or
- Liver disease—Rosiglitazone may make these conditions worse .
- Fragile bones (especially women)—Use with caution. This medicine may increase the risk of fractures .
- Heart disease or
- Heart surgery in the past or
- History of heart attacks or
- Other heart problems—This medicine may increase the risk of heart attacks and make these conditions worse
- Heart failure, severe —This medicine should not be used in patients with this condition .