Rabeprazole (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Bloating or swelling of the face, arms, hands, lower legs, or feet
• Cough or hoarseness
• Dark urine
• Dry mouth
• Fever or chills
• General tiredness and weakness
• Light-colored stools
• Lower back or side pain
• Nausea and vomiting
• Painful or difficult urination
• Rapid weight gain
• Tingling of the hands or feet
• Unusual weight gain or loss
• Yellow eyes and skin

• Bloody urine
• Continuing ulcers or sores in the mouth
• Convulsions (seizures)
• Difficulty with breathing
• Sore throat
• Unusual bleeding or bruising
• Unusual tiredness or weakness

• Back, leg, or stomach pains
• Bleeding gums
• Blood in the urine or stools
• Bloody, black, or tarry stools
• Change in consciousness
• Clay-colored stools
• Cloudy urine
• Confusion about identity, place, person, and time
• Continuing nausea or vomiting
• Difficulty with swallowing
• Dizziness
• Drowsiness
• Fast heartbeat
• General body swelling
• General feeling of tiredness or weakness
• Greatly decreased frequency of urination or amount of urine
• Headache
• High fever
• Hives
• Holding false beliefs that cannot be changed by fact
• Increase in the frequency of seizures
• Itching
• Joint or muscle pain
• Large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
• Loss of appetite
• Loss of consciousness
• Mood or mental changes
• Muscle cramps
• Muscle pain or stiffness
• Muscle spasms (tetany) or twitching
• No blood pressure
• No breathing
• No pulse
• Nosebleeds
• Pale skin
• Pinpoint red spots on the skin
• Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• Seeing, hearing, or feeling things that are not there
• Seizures
• Shortness of breath
• Skin blisters
• Skin rash
• Sores, ulcers, or white spots on the lips or in the mouth
• Swollen glands
• Tightness in the chest
• Trembling
• Unpleasant breath odor
• Unusual excitement, nervousness, or restlessness
• Vomiting of blood
• Wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Bad, unusual, or unpleasant (after) taste
• Change in taste

• Body aches or pain
• Congestion
• Constipation
• Diarrhea
• Excess air or gas in the stomach or intestines
• Feeling weak
• Full feeling
• Heartburn
• Numbness, tingling, pain, or weakness in the hands or feet
• Pain
• Passing gas
• Runny nose
• Sleepiness
• Swollen joints
• Tender, swollen glands in the neck
• Trouble with swallowing
• Voice changes

• Blistering, peeling, or loosening of the skin
• Red, irritated eyes
• Red skin lesions, often with a purple center

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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