Topiramate (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Any vision problems, especially blurred vision, double vision, eye pain, or rapidly decreasing vision
• Burning, prickling, or tingling sensations
• Clumsiness or unsteadiness
• Confusion
• Continuous, uncontrolled back-and-forth or rolling eye movements
• Dizziness
• Drowsiness
• Eye redness
• Generalized slowing of mental and physical activity
• Increased eye pressure
• Memory problems
• Menstrual changes
• Menstrual pain
• Nervousness
• Speech or language problems
• Trouble in concentrating or paying attention
• Unusual tiredness or weakness

• Abdominal or stomach pain
• Fever, chills, or sore throat
• Lessening of sensations or perception
• Loss of appetite
• Mood or mental changes, including aggression, agitation, apathy, irritability, and mental depression
• Red, irritated, or bleeding gums
• Weight loss

• Blood in the urine
• Decrease in sexual performance or desire
• Difficult or painful urination
• Eye pain
• Frequent urination
• Hearing loss
• Itching
• Loss of bladder control
• Lower back or side pain
• Nosebleeds
• Pale skin
• Red or irritated eyes
• Ringing or buzzing in the ears
• Skin rash
• Swelling
• Troubled breathing

• Blistering, peeling, or loosening of the skin
• Blisters in the mouth
• Blisters on the trunk, scalp, or other areas
• Bloating
• Clay-colored stools
• Constipation
• Cough
• Diarrhea
• Increased rate of breathing
• Itching
• Joint or muscle pain
• Pain or tenderness in upper abdomen or stomach
• Red skin lesions, often with a purple center
• Sores, ulcers, or white spots in the mouth or on the lips
• Yellow eyes or skin

Get emergency help immediately if any of the following symptoms of overdose occur:

• Decreased awareness or responsiveness
• Dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• Drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
• Muscle tremors
• Nausea
• Rapid, deep breathing
• Restlessness
• Severe sleepiness
• Stomach cramps
• Sweating unusual

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Breast pain in women
• Tremors

• Back pain
• Chest pain
• Constipation
• Heartburn
• Hot flushes
• Increased sweating
• Leg pain

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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