Leflunomide (Oral Route)

Free

E-newsletter

Subscribe to Housecall

Our weekly general interest
e-newsletter keeps you up to date on a wide variety of health topics.

Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Bloody or cloudy urine
• Cough
• Difficult or painful breathing
• Difficult, burning, or painful urination
• Dizziness
• Fever
• Frequent urge to urinate
• Headache
• Loss of appetite
• Nausea or vomiting
• Sneezing
• Sore throat
• Tightness in the chest
• Yellow eyes or skin

• Burning feeling in the chest or stomach
• Burning, prickling, or tingling sensation in the fingers or toes
• Chest pain
• Diarrhea
• Fast heartbeat
• Indigestion
• Joint or muscle pain or stiffness
• Pounding heartbeat
• Severe stomach pain
• Shortness of breath
• Tenderness in the stomach area
• Unusual tiredness or weakness

• Area rash
• Black or tarry stools
• Bleeding gums
• Blistering, peeling, or loosening of the skin
• Bloating
• Blood in the stools
• Burning, numbness, tingling, or painful sensations
• Chills
• Clay-colored stools
• Confusion
• Constipation
• Continuing vomiting
• Cough or hoarseness
• Dark urine
• Fainting
• Fever with or without chills
• General feeling of tiredness or weakness
• High fever
• Large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
• Light-colored stools
• Lightheadedness
• Lower back or side pain
• Pains in the stomach, side, or abdomen, possibly radiating to the back
• Pale skin
• Pinpoint red spots on the skin
• Rapid, shallow breathing
• Red skin lesions, often with a purple center
• Red, irritated eyes
• Sores, ulcers, or white spots in the mouth or on the lips
• Swollen glands
• Unexplained bleeding or bruising
• Unpleasant breath odor
• Unsteadiness or awkwardness
• Unusual bleeding or bruising
• Upper right abdominal or stomach pain
• Vomiting of blood
• Weakness in the arms, hands, legs, or feet

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Back pain
• Hair loss
• Heartburn
• Skin rash
• Stomach pain
• Weight loss (unexplained)

• Acne
• Anxiety
• Decreased appetite
• Dry mouth
• Gas
• Irritation or soreness of the mouth
• Itching of the skin
• Pain or burning in the throat
• Runny nose

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Copyright © 2013 Thomson Healthcare Inc. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.