Mayo Clinic Health Manager
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Calcipotriene may cause irritation of the affected area(s) of your skin for a short time after you have applied it. Sometimes it may also cause irritation of the surrounding normal skin. If this happens, try not to scratch the area.
If the irritation continues, if you develop rash on your face, or if the medicine causes any other problems for you, stop using the medicine and check with your doctor.
You may have to see your doctor regularly while using this medicine so that your doctor can check for any side effects, especially an increase in the level of calcium in your blood or urine, because this may lead to kidney stone formation.
Your doctor may tell you when you should expect to notice an improvement in your condition (usually within 2 to 8 weeks). If your condition has not improved by then or if it becomes worse, check with your doctor.
Calcipotriene may cause your skin to be more sensitive to sunlight than it is normally. Exposure to sunlight, even for brief periods of time, may cause a skin rash, itching, redness, or other discoloration of the skin, or a severe sunburn. When you begin taking this medicine:
- Stay out of direct sunlight, especially between the hours of 10:00 a.m. and 3:00 p.m., if possible
- Wear protective clothing, including a hat. Also, wear sunglasses.
- Apply a sunblock product that has a skin protection factor (SPF) number, especially if you have a fair complexion. If you have any questions about this, check with your health care professional
- Do not use a sun lamp or tanning bed or booth.
If you have a severe reaction from the sun, check with your doctor.