Stavudine (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Burning, numbness, tingling, or painful sensations
• Chills with fever
• Tingling, burning, numbness, or pain in the hands or feet
• Unsteadiness or awkwardness
• Weakness in the arms, hands, legs, or feet

• Cough
• Difficulty with swallowing
• Dizziness
• Fast heartbeat
• Hives
• Itching
• Joint pain
• Muscle pain
• Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• Shortness of breath
• Skin rash
• Tightness in the chest
• Unusual tiredness or weakness
• Wheezing

• Nausea and vomiting
• Stomach pain (severe)

• Abdominal or stomach discomfort or pain
• Black, tarry stools
• Bleeding gums
• Bloating
• Blood in the urine or stools
• Blurred vision
• Chest pain
• Constipation
• Darkened urine
• Decreased appetite
• Diarrhea
• Difficulty with moving
• Dry mouth
• Fast, shallow breathing
• Fever
• Flushed, dry skin
• Fruit-like breath odor
• General feeling of discomfort
• General tiredness and weakness
• Increased hunger
• Increased thirst
• Increased urination
• Indigestion
• Light-colored stools
• Loss of appetite
• Loss of consciousness
• Muscle cramping, pains, or stiffness
• Painful or difficult urination
• Pains in the stomach, side, or abdomen, possibly radiating to the back
• Pale skin
• Pinpoint red spots on the skin
• Shakiness and unsteady walk, unsteadiness, trembling, or other problems with muscle control or coordination
• Sleepiness
• Sore throat
• Sores, ulcers, or white spots on the lips or in the mouth
• Sweating
• Swollen glands
• Swollen joints
• Troubled breathing
• Troubled breathing with exertion
• Unexplained weight loss
• Unusual bleeding or bruising
• Yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Headache
• Loss of appetite
• Weight loss

• Difficulty with sleeping
• Lack of strength or energy
• Stomach pain (mild)

• Gaining weight around your neck, upper back, breast, face, or waist
• Sleeplessness
• Unable to sleep

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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