Cyclosporine (Oral Route, Intravenous Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Some side effects will have signs or symptoms that you can see or feel. Your doctor will watch for others by doing certain tests.

Also, because of the way that cyclosporine acts on the body, there is a chance that it may cause effects that may not occur until years after the medicine is used. These delayed effects may include certain types of cancer, such as lymphomas or skin cancers. You and your doctor should discuss the good this medicine will do as well as the risks of using it.

Check with your doctor immediately if any of the following side effects occur:

Rare
  • Blood in urine
  • Flushing of face and neck (for injection only)
  • Wheezing or shortness of breath (for injection only)

Check with your doctor as soon as possible if any of the following side effects occur:

More common
  • Bleeding, tender, or enlarged gums
Less common
  • Convulsions (seizures)
  • Fever or chills
  • Frequent urge to urinate
  • Vomiting
Rare
  • Confusion
  • General feeling of discomfort and illness
  • Irregular heartbeat
  • Numbness or tingling in hands, feet, or lips
  • Shortness of breath or difficult breathing
  • Stomach pain (severe) with nausea and vomiting
  • Unexplained nervousness
  • Unusual tiredness or weakness
  • Weakness or heaviness of legs
  • Weight loss
Incidence not known
  • Agitation
  • Back pain
  • Blurred vision
  • Coma
  • Dizziness
  • Drowsiness
  • Hallucinations
  • Irritability
  • Mood or mental changes
  • Seizures
  • Stiff neck

This medicine may also cause the following side effects that your doctor will watch for:

More common
  • High blood pressure
  • Kidney problems
Less common
  • Changes in blood chemistry
  • Liver problems

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Increase in hair growth
  • Trembling and shaking of hands
Less common
  • Acne or oily skin
  • Headache
  • Leg cramps
  • Nausea

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Precautions

DR601591

Portions of this document last updated:

Nov. 1, 2009

Source: Drug Information provided by: Micromedex

Copyright © 2009 Thomson Healthcare Inc. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.


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