Fondaparinux (Subcutaneous Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Pale skin
• Troubled breathing with exertion
• Unusual bleeding or bruising
• Unusual tiredness or weakness

• Black, tarry stools
• Bladder pain
• Bleeding
• Bleeding gums
• Blood in the urine or stools
• Blurred vision
• Chest pain
• Chills
• Collection of blood under the skin
• Confusion
• Convulsions
• Cough
• Decreased or cloudy urine
• Deep, dark purple bruise
• Difficult, burning, or painful urination
• Dizziness
• Dry mouth
• Fainting or lightheadedness when getting up from a lying or sitting position
• Fever
• Frequent urge to urinate
• Increased thirst
• Irregular heartbeat
• Itching, pain, redness, or swelling at the place of injection
• Loss of appetite
• Lower back or side pain
• Mood changes
• Muscle pain or cramps
• Nausea or vomiting
• Numbness or tingling in the hands, feet, or lips
• Pinpoint red spots on the skin
• Red, tender, or oozing skin at incision
• Shortness of breath
• Sore throat
• Sores, ulcers, or white spots on the lips or in the mouth
• Sudden sweating

Get emergency help immediately if any of the following symptoms of overdose occur:

• Abdominal or stomach pain or swelling
• Bruising or purple areas on the skin
• Coughing up blood
• Decreased alertness
• Headache
• Joint pain or swelling
• Nosebleeds

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Difficulty having a bowel movement
• Rash
• Sleeplessness
• Swelling
• Trouble sleeping

• Acid or sour stomach
• Belching
• Diarrhea
• Heartburn
• Indigestion
• Pain
• Skin blisters
• Stomach discomfort, upset, or pain
• Tightness in the chest
• Unusual changes to site of surgery
• Wheezing
• Wound drainage, increased

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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