Galsulfase (Intravenous Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

• Blindness
• Blurred vision
• Chest pain
• Decreased vision
• Difficult or labored breathing
• Dizziness
• Headache
• Hernia of the naval
• Nervousness
• Pounding in the ears
• Shortness of breath
• Slow or fast heartbeat
• Swelling of the face
• Tightness in the chest
• Wheezing

• Bluish lips or skin
• Confusion
• Cough
• Dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• Fever or chills
• Hives or welts
• Itching
• Joint pain
• Large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
• Nausea
• Noisy breathing
• Not breathing
• Pain behind the sternum or breastbone
• Redness of the skin
• Skin rash
• Stomach pain
• Sweating
• Troubled breathing
• Vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Body produces substance that can bind to drug making it less effective or cause side effects
• Diarrhea
• Ear pain
• Loss of appetite
• Pain
• Stomach pain

• Body aches or pain
• Burning, dry, or itching eyes
• Congestion
• Discharge
• Dryness or soreness of the throat
• Excessive tearing
• General feeling of discomfort or illness
• Hoarseness
• Loss of or increase in reflexes
• Redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid
• Runny or stuffy nose
• Tender, swollen glands in the neck
• Trouble with swallowing
• Unusual tiredness or weakness
• Voice changes

• Difficulty with moving
• Ear congestion
• Loss of voice
• Muscle pain or stiffness
• Nasal congestion
• Redness or swelling in the ear
• Sneezing

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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