Paclitaxel Protein-Bound (Intravenous Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common
  • Black, tarry stools
  • Blurred or double vision
  • Chest pain
  • Chills
  • Cough
  • Fever
  • Loss of taste
  • Lower back or side pain
  • Painful or difficult urination
  • Pale skin
  • Shortness of breath
  • Sneezing
  • Sore mouth or tongue
  • Sore throat
  • Tightness in the chest
  • Troubled breathing with exertion
  • Ulcers, sores, or white spots in the mouth
  • Unusual bleeding or bruising
  • Unusual tiredness or weakness
  • Wheezing
  • White patches in the mouth or on the tongue
Less common
  • Abnormal electrocardiogram (ECG)
  • Anxiety
  • Bleeding
  • Bleeding gums
  • Blood in the urine or stools
  • Burning, tingling, numbness or pain in the hands, arms, feet, or legs
  • Confusion
  • Difficulty with breathing
  • Difficulty with swallowing
  • Dizziness or lightheadedness
  • Dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
  • Fainting
  • Fast, pounding, or irregular heartbeat or pulse
  • Low blood pressure or slow pulse
  • Pain in the chest, groin, or legs, especially the calves
  • Palpitations
  • Pinpoint red spots on the skin
  • Sensation of pins and needles
  • Severe, sudden headache
  • Skin itching, rash, or redness
  • Slow or irregular heartbeat
  • Slurred speech
  • Stabbing pain
  • Sudden loss of coordination
  • Sudden, severe weakness or numbness in the arms or legs
  • Sudden, unexplained shortness of breath
  • Sweating
  • Swelling of the face, throat, or tongue
  • Tenderness, pain, swelling, warmth, skin discoloration, and prominent superficial veins over the affected area
  • Unconsciousness
  • Vision changes
Rare
  • Difficulty with speaking
  • Headache
  • Inability to move the arms, legs, or facial muscles
  • Inability to speak
  • Numbness or tingling in the face, arms, or legs
  • Severe pain in the chest
  • Slow speech
  • Sudden onset of severe breathing problems
  • Trouble speaking, thinking, or walking

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Cracked lips
  • Diarrhea
  • Difficulty with moving
  • Lack or loss of strength
  • Loss of hair
  • Muscle pain or stiffness
  • Nausea
  • Pain in the joints
  • Swelling
  • Vomiting
Less common
  • Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the site of injection
Rare
  • Nail changes
Observed during clinical trials
  • Disturbed color perception with your eyes
  • Halos around lights
  • Loss of vision
  • Night blindness
  • Overbright appearance of lights
  • Tunnel vision

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Precautions

DR601657

Portions of this document last updated:

Nov. 1, 2009

Source: Drug Information provided by: Micromedex

Copyright © 2009 Thomson Healthcare Inc. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.


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