Mayo Clinic Health Manager
Get free personalized health guidance for you and your family.
Get Started
About our e-newsletters
- Free e-newsletters
- Mayo Clinic expertise
- We do not share your e-mail address
Housecall, our weekly general-interest e-newsletter, keeps you up to date on a wide variety of health topics with timely, reliable, practical information, recipes, blogs, questions and answers with Mayo Clinic experts and more. Our biweekly topic-specific e-newsletters also include blogs, questions and answers with Mayo Clinic experts, and other useful information that will help you manage your health.
Housecall Archives
Mayo Clinic Housecall
Stay up to date on the latest health information.
What you get
- Free weekly e-newsletter
- Mayo Clinic expertise
- Recipes, tools and other helpful information
- We do not share your e-mail address
Before Using
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of carvedilol in the pediatric population. Safety and efficacy have not been established.
Geriatric
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of carvedilol in the elderly.
Pregnancy
| Pregnancy Category | Explanation | |
|---|---|---|
| All Trimesters | C | Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women. |
Breastfeeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Drug Interactions
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Albuterol
- Amiodarone
- Arformoterol
- Bambuterol
- Bitolterol
- Broxaterol
- Clenbuterol
- Clonidine
- Colterol
- Diltiazem
- Dronedarone
- Epinephrine
- Fenoldopam
- Fenoterol
- Fentanyl
- Formoterol
- Hexoprenaline
- Isoetharine
- Levalbuterol
- Metaproterenol
- Pirbuterol
- Procaterol
- Reproterol
- Rimiterol
- Ritodrine
- Salmeterol
- Terbutaline
- Tretoquinol
- Tulobuterol
- Verapamil
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Acarbose
- Acetohexamide
- Alfuzosin
- Amlodipine
- Arbutamine
- Benfluorex
- Bunazosin
- Chlorpropamide
- Cimetidine
- Digoxin
- Dobutamine
- Doxazosin
- Felodipine
- Gliclazide
- Glimepiride
- Glipizide
- Gliquidone
- Glyburide
- Guar Gum
- Insulin
- Insulin Aspart, Recombinant
- Insulin Glulisine
- Insulin Lispro, Recombinant
- Lacidipine
- Lercanidipine
- Manidipine
- Metformin
- Mibefradil
- Miglitol
- Moxisylyte
- Nicardipine
- Nifedipine
- Nilvadipine
- Nimodipine
- Nisoldipine
- Nitrendipine
- Phenoxybenzamine
- Phentolamine
- Pranidipine
- Prazosin
- Repaglinide
- Rifampin
- Rifapentine
- St John's Wort
- Tamsulosin
- Terazosin
- Tolazamide
- Tolbutamide
- Trimazosin
- Troglitazone
- Urapidil
Other Interactions
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
- Angina (severe chest pain) or
- Bradycardia (slow heartbeat) or
- Breathing or other lung problems (e.g., bronchitis or emphysema) or
- Coronary artery disease or
- Diabetes or
- Edema (fluid retention or body swelling) or
- Heart or blood vessel disease or
- Hypotension (low blood pressure) or
- Major surgery, scheduled or
- Overactive thyroid or
- Peripheral vascular disease or
- Pheochromocytoma (adrenal gland tumor)—Use with caution. May make these conditions worse.
- Asthma or
- AV block, second or third-degree or
- Bradycardia (slow heartbeat), severe or
- Heart failure, decompensated or
- Hypersensitivity reactions (e.g., anaphylaxis, angioedema, Stevens-Johnson syndrome) or
- Liver disease, severe or
- Shock or
- Sick sinus syndrome—Should not be used in patients with these conditions.
- Low blood sugar (hypoglycemia)—May aggravate low blood sugar (hypoglycemia) levels caused by insulin and may delay recovery of blood sugar levels; in patients with diabetes and heart failure, carvedilol may further increase blood sugar levels; in addition, if your diabetes medicine causes your blood sugar to be too low, carvedilol may cover up some of the symptoms (fast heartbeat).
- Kidney disease or
- Liver disease—Use with caution. Effects may be increased because of slower removal of the medicine from the body.
