Immune Globulin (Intramuscular Route, Intravenous Route, Subcutaneous Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

• Chills
• Cough
• Difficulty with breathing
• Fast, pounding, or irregular heartbeat or pulse
• Fever
• Noisy breathing
• Shortness of breath
• Tightness in the chest
• Troubled breathing
• Unusual tiredness or weakness

• Bluish coloring of the lips or nailbeds
• Burning sensation in the head
• Faintness or lightheadedness

• Difficulty with swallowing
• Hives or welts
• Itching, especially of the feet or hands
• Reddening of the skin, especially around the ears
• Swelling of the eyes, face, or inside of the nose

• Back, leg, or stomach pains
• Bleeding gums
• Blistering, peeling, or loosening of the skin
• Bloody, black, or tarry stools
• Blurred vision
• Change in consciousness
• Chest pain or discomfort
• Cold, clammy, or pale skin
• Confusion
• Convulsions
• Coughing that sometimes produces a pink frothy sputum
• Dark urine
• Decrease in urine amount
• Dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• Fever with or without chills
• Headache that is severe and occurs suddenly
• Increased sweating
• Light-colored stools
• Loss of appetite
• Loss of bladder control
• Loss of consciousness
• Low blood pressure or pulse
• Muscle spasm or jerking of all extremities
• Nausea or vomiting
• Nosebleeds
• Painful or difficult urination
• Pains in the chest, groin, or legs, especially calves of the legs
• Red skin lesions, often with a purple center
• Red, irritated eyes
• Shakiness in the legs, arms, hands, or feet
• Shivering
• Skin blisters
• Slurred speech that occurs suddenly
• Slow breathing
• Sores, ulcers, or white spots in the mouth or on the lips
• Sudden loss of consciousness
• Sudden loss of coordination
• Sudden vision changes
• Sudden, severe weakness or numbness in the arm or leg
• Sweating
• Swelling in the legs and ankles
• Tightness in the chest
• Trembling or shaking of the hands or feet
• Unusual bleeding or bruising
• Yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Diarrhea
• Dizziness
• Headache
• Joint pain
• Muscle pain
• Redness, swelling, itching, or pain at the injection site
• Skin rash

• Hip pain
• Leg cramps

• Feeling of warmth
• Redness of the face, neck, arms, and occasionally, upper chest
• Stomach pain
• Swollen glands
• Tiredness
• Weakness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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