Octreotide (Injection Route, Intramuscular Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

• Abdominal or stomach pain
• Blurred vision
• Constipation
• Depressed mood
• Dizziness
• Dry mouth
• Dry skin and hair
• Fainting
• Fast, slow, or irregular heartbeat
• Feeling cold
• Flushed, dry skin
• Fruit-like breath odor
• Hair loss
• Hoarseness or husky voice
• Increased hunger
• Increased thirst
• Increased urination
• Muscle cramps and stiffness
• Nausea
• Severe stomach pain with nausea and vomiting
• Sweating
• Troubled breathing
• Unexplained weight loss
• Unusual tiredness or weakness
• Vomiting
• Weight gain

• Abdominal or stomach bloating
• Anxious feeling
• Behavior change similar to drunkenness
• Changes in menstrual periods
• Cold sweats
• Confusion
• Convulsions (seizures)
• Cool, pale skin
• Decreased sexual ability in males
• Difficulty with concentrating
• Drowsiness
• Headache
• Loss of appetite
• Muscle cramps and stiffness
• Nightmares
• Restless sleep
• Shakiness
• Slurred speech
• Swelling of the front part of the neck
• Tiredness
• Troubled breathing (rapid and deep)
• Unconsciousness
• Unusual thirst

• Black, tarry stools
• Bleeding gums
• Blood in the urine or stools
• Chills
• Darkened urine
• Fever
• Indigestion
• Pains in the stomach, side, or abdomen, possibly radiating to the back
• Pinpoint red spots on the skin
• Severe constipation
• Unusual bleeding or bruising
• Yellow eyes or skin

Get emergency help immediately if any of the following symptoms of overdose occur:

• Abdominal or stomach discomfort
• Decreased appetite
• Diarrhea
• Dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• Fast, shallow breathing
• Feeling of warmth
• General feeling of discomfort
• Light-colored stools
• Muscle pain or cramping
• No blood pressure or pulse
• Redness of the face, neck, arms, and occasionally, upper chest
• Shortness of breath
• Sleepiness
• Stopping of heart
• Unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
• Upper right abdominal or stomach pain
• Weakness
• Weight loss

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Pain, redness, stinging, swelling, tingling, or burning sensation at the injection site
• Passing of gas

• Backache
• Bladder pain
• Cloudy urine
• Cough
• Difficult, burning, or painful urination
• Disturbed color perception
• Double vision
• Frequent urge to urinate
• Frequent urination usually with very small amounts of urine
• General feeling of discomfort or illness
• Halos around lights
• Itching skin
• Joint pain
• Lack of appetite
• Loss of vision
• Lower back or side pain
• Muscle aches and pains
• Night blindness
• Overbright appearance of lights
• Runny nose
• Shivering
• Sore throat
• Stools that float, are foul smelling, and fatty in appearance
• Trouble concentrating
• Trouble sleeping
• Tunnel vision

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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