Octreotide (Injection Route, Intramuscular Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Changes in menstrual periods
• Convulsions (seizures)
• Decreased sexual ability in males
• Depressed mood
• Dry skin and hair
• Dry, puffy skin
• Feeling cold
• Hoarseness or husky voice
• Muscle cramps and stiffness
• Slowed heartbeat
• Swelling of front part of neck
• Unconsciousness
• Unusual tiredness or weakness
• Weight gain

Check with your doctor as soon as possible if any of the following side effects occur:

• Irregular heartbeat
• Slow heartbeat

• Hyperglycemia (high blood sugar), including blurred vision, drowsiness, dry mouth, flushed dry skin, fruit-like breath odor, increased urination (frequency and volume), ketones in urine, loss of appetite, nausea, stomachache, tiredness, troubled breathing (rapid and deep), unusual thirst, or vomiting
• Hypoglycemia (low blood sugar), including anxious feeling, behavior change similar to drunkenness, blurred vision, cold sweats, confusion, cool pale skin, difficulty in concentrating, drowsiness, excessive hunger, fast heartbeat, headache, nausea, nervousness, nightmares, restless sleep, shakiness, slurred speech, or unusual tiredness or weakness
• Inflammation of the pancreas gland, including abdominal or stomach pain or bloating, nausea, or vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Constipation
• Diarrhea
• Headache
• Pain, stinging, tingling, or burning sensation at place of injection, with redness and swelling
• Passing of gas

• Backache
• Bladder pain
• Bloody or cloudy urine
• Blurred or loss of vision
• Chills
• Cough
• Difficult, burning, or painful urination
• Discouragement
• Disturbed color perception
• Dizziness or light-headedness
• Double vision
• Feeling sad or empty
• Fever
• Frequent urge to urinate
• Frequent urination usually with very small amounts of urine
• General feeling of discomfort or illness
• Hair loss
• Halos around lights
• Irritability
• Itching skin
• Joint pain
• Lack or loss of appetite
• Loss of interest or pleasure
• Lower back or side pain
• Muscle aches and pains
• Nausea
• Night blindness
• Overbright appearance of lights
• Redness or flushing of face
• Runny nose
• Shivering
• Sore throat
• Stools that float, are foul smelling, and fatty in appearance
• Sweating
• Swelling of feet or lower legs
• Tiredness
• Trouble concentrating
• Trouble sleeping
• Tunnel vision
• Vomiting

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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