It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly and to check for unwanted effects.
While you are being treated with asparaginase, and after you stop treatment with it, do not have any immunizations (vaccinations) without your doctor's approval. Asparaginase may lower your body's resistance and there is a chance you might get the infection the immunization is meant to prevent. In addition, other persons living in your household should not take oral polio vaccine since there is a chance they could pass the polio virus on to you. Also, avoid persons who have taken oral polio vaccine within the last several months. Do not get close to them, and do not stay in the same room with them for very long. If you cannot take these precautions, you should consider wearing a protective face mask that covers the nose and mouth.
Before you have any medical tests, tell the medical doctor in charge that you are receiving this medicine. The results of thyroid tests may be affected by this medicine.