Danazol (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Acne
• Dark-colored urine
• Increased oiliness of the hair or skin
• Muscle cramps or spasms
• Rapid weight gain
• Swelling of the feet or lower legs
• Unusual tiredness or weakness

• Bleeding gums
• Bloating, pain, or tenderness of the abdomen or stomach
• Blood in the urine
• Burning, numbness, pain, or tingling in all fingers except the smallest finger
• Changes in vision
• Chest pain
• Chills
• Complete or partial numbness or weakness on one side of body
• Cough
• Coughing up blood
• Diarrhea
• Difficulty with speaking
• Difficulty with swallowing
• Discharge from the nipple
• Eye pain
• Fast heartbeat
• Fever
• Headache
• Hives or other skin rash
• Joint pain
• Light-colored stools
• Loss of appetite (continuing)
• Loss of muscle coordination
• More frequent nosebleeds
• Muscle aches
• Nausea
• Purple- or red-colored, or other spots on the body or inside the mouth or nose
• Restlessness
• Shortness of breath
• Sore throat
• Sweating
• Tingling, numbness, or weakness in the legs, which may move upward to the arms, trunk, or face
• Unusual bruising or bleeding
• Unusual tiredness, weakness, or general feeling of illness
• Vomiting
• Yellow eyes or skin

• Decrease in the breast size
• Irregular menstrual periods
• Weight gain

• Enlarged clitoris
• Hoarseness or deepening of voice
• Unnatural hair growth

• Changes in semen
• Decrease in the size of the testicles

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Flushing or redness of the skin
• Mood or mental changes
• Nervousness

• Increased sensitivity of the skin to sunlight

• Burning, dryness, or itching of the vagina
• Vaginal bleeding

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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