Levetiracetam (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Aggressive or angry
• Anxiety
• Change in personality
• Chills
• Cough or hoarseness
• Crying
• Depersonalization
• Diarrhea
• Dry mouth
• Euphoria
• Fever
• General feeling of discomfort or illness
• Headache
• Hyperventilation
• Irregular heartbeats
• Irritability
• Joint pain
• Loss of appetite
• Lower back or side pain
• Mental depression
• Muscle aches and pains
• Nausea
• Nervousness
• Painful or difficult urination
• Paranoia
• Quick to react or overreact emotionally
• Rapidly changing moods
• Restlessness
• Shaking
• Shivering
• Shortness of breath
• Sleepiness or unusual drowsiness
• Sore throat
• Stuffy or runny nose
• Sweating
• Trouble with sleeping
• Unusual tiredness or weakness
• Vomiting

• Bloody nose
• Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
• Clumsiness or unsteadiness
• Discouragement
• Dizziness or lightheadedness
• Double vision
• Earache
• Fear or nervousness
• Feeling of constant movement of self or surroundings
• Feeling sad or empty
• Increase in body movements
• Loss of bladder control
• Loss of memory
• Mood or mental changes
• Outburst of anger
• Pain or tenderness around the eyes and cheekbones
• Problems with memory
• Redness or swelling in the ear
• Seizures
• Sensation of spinning
• Shakiness and unsteady walk
• Shakiness in the legs, arms, hands, or feet
• Tightness of the chest or wheezing
• Tiredness
• Trembling or shaking of the hands or feet
• Trouble concentrating
• Unsteadiness, trembling, or other problems with muscle control or coordination

• Attempts at killing oneself
• Being forgetful
• Bleeding gums
• Blistering, peeling, or loosening of the skin
• Bloating
• Blood in the urine or stools
• Bloody, black, or tarry stools
• Blurred vision
• Changes in vision
• Chest pain
• Constipation
• Dark urine
• Difficulty with moving
• Fast heartbeat
• General feeling of tiredness or weakness
• High fever
• Increase in body movements
• Indigestion
• Itching
• Light-colored stools
• Muscle pains or stiffness
• Painful or difficult urination
• Pains in the stomach, side, or abdomen, possibly radiating to the back
• Pale skin
• Pinpoint red spots on the skin
• Red skin lesions, often with a purple center
• Red, irritated eyes
• Sores, ulcers, or white spots on the lips or in the mouth
• Stomach pain, continuing
• Swollen glands
• Swollen joints
• Thoughts or attempts at killing oneself
• Trouble with balance
• Twitching, twisting, or uncontrolled repetitive movements of the tongue, lips, face, arms, or legs
• Uncontrolled jerking or twisting movements of the hands, arms, or legs
• Uncontrolled movements of the lips, tongue, or cheeks
• Unexplained bleeding or bruising
• Unusual bleeding or bruising
• Upper right abdominal or stomach pain
• Weight loss
• Yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Loss of strength or energy
• Muscle pain or weakness
• Pain
• Tender, swollen glands in the neck
• Trouble with swallowing
• Unusual weak feeling
• Voice changes

• Body aches or pain
• Burning, dry, or itching eyes
• Change in the color of the skin
• Congestion
• Cough increased
• Rash
• Sneezing

• Hair loss or thinning of the hair
• Skin rash, encrusted, scaly, and oozing

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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