Rituximab (Intravenous Route)
Drug Information provided by: MicromedexUS Brand Names
|
Description
Rituximab injection is a monoclonal antibody. It is used to treat a type of cancer called non-Hodgkin's lymphoma (NHL). It can be used alone or with other cancer medicines (chemotherapy). It is also used as a "maintenance" treatment for patients with advanced follicular lymphoma who responded to initial treatment with this medicine plus chemotherapy (induction treatment).
Rituximab is also used in combination with fludarabine and cyclophosphamide (FC) for the treatment of chronic lymphocytic leukemia (CLL).
Rituximab may also be used in combination with methotrexate to reduce the signs and symptoms of rheumatoid arthritis and help keep joint damage from getting worse after at least one other medicine (e.g., adalimumab, etanercept, infliximab) has been used and did not work well.
Rituximab is also used in combination with glucocorticoids to treat Wegener's granulomatosis (WG) and microscopic polyangiitis (MPA).
This medicine is to be administered only by or under the immediate supervision of your doctor.
Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, rituximab is used in certain patients with the following medical conditions:
- Immune or idiopathic thrombocytopenic purpura (ITP) (a blood disease).
- Waldenstrom's macroglobulinemia (cancer of the blood).

Find Mayo Clinic on