Tacrolimus (Topical Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Incidence not known
  • Agitation
  • Black, tarry stools
  • Bloody urine
  • Burning or stinging sensation of face
  • Change in size, shape, or color of existing mole
  • Coma
  • Confusion
  • Convulsions
  • Decreased frequency/amount of urine
  • Depression
  • Fever
  • General feeling of illness
  • Growth or bump on skin
  • Hostility
  • Increase in bone pain
  • Increased blood pressure
  • Increased thirst
  • Irritability
  • Lethargy
  • Looks very ill
  • Loss of appetite
  • Loss of bladder control
  • Lower back/side pain
  • Mole that leaks fluid or bleeds
  • Muscle spasm or jerking of all extremities
  • Muscle twitching
  • Nausea
  • New mole
  • Rapid weight gain
  • Red rash with watery, yellow-colored, or pus filled blisters
  • Redness of face
  • Seizures
  • Small, red skin lesion, growth, or bump usually on face, ears, neck, hands, or arms
  • Sore that will not heal
  • Spider-like blood vessels on the face
  • Stupor
  • Sudden loss of consciousness
  • Swelling of face, ankles, lower legs, hands, or fingers
  • Swollen glands
  • Thick yellow to honey-colored crusts
  • Unusual tiredness or weakness
  • Vomiting
  • Weight gain
  • Weight loss
  • Yellow skin and eyes

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Cough
  • Fever
  • General aches and pains
  • Headache
  • Itching skin–in children
  • Loss of appetite
  • Skin burning
  • Skin flushing in areas of ointment application when drinking alcohol
  • Sneezing
  • Weakness
Less common
  • Acid or sour stomach
  • Acne
  • Back pain
  • Belching
  • Burning, itching, or pain in hairy areas
  • Chills
  • Cyst
  • Flushing
  • Heartburn
  • Increased sensitivity to sunlight
  • Increased skin sensitivity
  • Indigestion
  • Itching eyes
  • Joint pain
  • Muscle aches or pain
  • Pain in eye
  • Pain or tenderness around eyes and cheekbones
  • Pus at root of hair
  • Rash
  • Redness in eye
  • Runny nose
  • Severe skin rash or hives
  • Skin blisters—in children
  • Skin tingling
  • Stomach discomfort, upset, or pain
  • Stuffy nose
  • Swelling of eye, eyelid, or inner lining of eyelid
  • Swollen glands
  • Tightness of chest
  • Troubled breathing or wheezing
  • Watery eyes

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Precautions

DR601817

Portions of this document last updated:

Nov. 1, 2009

Source: Drug Information provided by: Micromedex

Copyright © 2009 Thomson Healthcare Inc. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.


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