Oxaliplatin (Intravenous Route)

Free

E-newsletter

Subscribe to Housecall

Our weekly general interest
e-newsletter keeps you up to date on a wide variety of health topics.

Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

• Abnormal tongue sensation
• Black, tarry stools
• Bleeding gums
• Blistering, peeling, redness, and/or swelling of the palms of the hands or bottoms of the feet
• Blood in the urine or stools
• Burning, prickling, itching, or tingling of the skin
• Chest pain
• Chills
• Confusion
• Cough
• Decreased feeling, or pain in the hands, feet, around the mouth, or throat
• Decreased urination
• Difficulty performing daily activities such as writing, buttoning, swallowing, or walking
• Difficulty with articulating words
• Difficulty with breathing
• Difficulty with moving
• Difficulty with swallowing
• Dizziness
• Dry mouth
• Eye pain
• Fainting
• Fever
• Increase in heart rate
• Jaw spasm
• Lightheadedness
• Muscle pain or stiffness
• Numbness
• Numbness, pain, tingling, or unusual sensations in the palms of the hands or bottoms of the feet
• Pain in the chest, groin, or legs, especially the calves
• Pain in the joints
• Painful or difficult urination
• Pale skin
• Pinpoint red spots on the skin
• Rapid breathing
• Sensation of pins and needles
• Severe, sudden headache
• Shortness of breath
• Slurred speech
• Sore throat
• Sores, ulcers, or white spots on the lips or in the mouth
• Stabbing pain
• Sudden loss of coordination
• Sudden, severe weakness or numbness in the arm or leg
• Sudden, unexplained shortness of breath
• Sunken eyes
• Swelling
• Swelling or inflammation of the mouth
• Swollen glands
• Thirst
• Troubled breathing with exertion
• Unusual bleeding or bruising
• Unusual tiredness or weakness
• Vision changes
• Wrinkled skin

• Convulsions
• Fast heartbeat
• Hives
• Increased thirst
• Irregular heartbeat
• Itching
• Loss of appetite
• Mood changes
• Nausea or vomiting
• Numbness or tingling in the hands, feet, or lips
• Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• Skin rash
• Tightness in the chest
• Wheezing

• Back, leg, or stomach pains
• Blindness
• Bloated abdomen
• Blue-yellow color blindness
• Blurred vision
• Changes in patterns and rhythms of speech
• Dark urine
• Deafness
• Decreased vision
• Deep breathing
• Drowsiness
• Electric shock-like sensation that moves down the back and into the legs following a bending movement of the neck
• General body swelling
• Increased urination
• Large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
• Loss of deep tendon reflexes
• Muscle tremors
• Pain and fullness in the right upper abdomen
• Restlessness
• Severe constipation
• Severe diarrhea
• Severe nosebleeds
• Severe stomach cramps or tenderness
• Severe vomiting
• Trouble with speaking
• Twitches of the muscle visible under the skin
• Weakness of the muscles in your face
• Weight gain
• Yellow eyes or skin

Get emergency help immediately if any of the following symptoms of overdose occur:

• Agitation
• Coma
• Cough or hoarseness
• Diarrhea
• Disorientation
• Involuntary, rapid, or rhythmic movement of the eyes
• Lack of coordination
• Lack of sensation
• Lethargy
• Lower back or side pain
• Paralysis
• Respiratory failure
• Seizures
• Severe weakness
• Slow or irregular heartbeat
• Tremors
• Vomiting, profuse

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Acid or sour stomach
• Belching
• Body aches or pain
• Ear congestion
• Feeling unusually cold, shivering
• Headache
• Heartburn
• Indigestion
• Loss of voice
• Nasal congestion
• Runny nose
• Sleeplessness
• Sneezing
• Stomach discomfort, upset, or pain
• Stuffy nose
• Trouble sleeping
• Unable to sleep
• Weight loss

• Bad, unusual, or unpleasant (after) taste
• Bloated, full feeling
• Bloody nose
• Burning while urinating
• Change in taste
• Congestion
• Cracked lips
• Dryness or soreness of the throat
• Excess air or gas in stomach or intestines
• Feeling of warmth
• Hair loss
• Passing gas
• Rapid weight gain
• Redness of the face, neck, arms, and occasionally upper chest
• Tender, swollen glands in the neck
• Thinning of the hair
• Unusual tearing of the eyes
• Voice changes

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Copyright © 2013 Thomson Healthcare Inc. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.