Cilostazol (Oral Route)

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Before Using

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Studies on this medicine have been done only in adult patients, and there is no specific information comparing the use of cilostazol in children with use in other age groups.

Geriatric

This medicine has been tested in a limited number of patients and has not been shown to cause different side effects or problems in older people than it does in younger adults.

Pregnancy

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Abciximab
• Alteplase, Recombinant
• Aspirin
• Bromfenac
• Celecoxib
• Citalopram
• Clopidogrel
• Dabigatran Etexilate
• Desirudin
• Desvenlafaxine
• Diclofenac
• Diflunisal
• Dipyridamole
• Duloxetine
• Eptifibatide
• Escitalopram
• Etodolac
• Fluoxetine
• Flurbiprofen
• Fluvoxamine
• Ginkgo
• Ibuprofen
• Ibuprofen Lysine
• Indomethacin
• Ketoprofen
• Ketorolac
• Magnesium Salicylate
• Mefenamic Acid
• Meloxicam
• Milnacipran
• Nabumetone
• Naproxen
• Nefazodone
• Nepafenac
• Oxaprozin
• Paroxetine
• Piroxicam
• Prasugrel
• Rivaroxaban
• Salsalate
• Sertraline
• Sulfinpyrazone
• Sulindac
• Ticlopidine
• Tirofiban
• Tolmetin
• Venlafaxine

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Clarithromycin
• Diltiazem
• Erythromycin
• Ketoconazole
• Omeprazole

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

• Grapefruit Juice

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Active bleeding (including peptic ulcers and intracranial bleeding [e.g., bleeding on the brain]) or
• Blood or blood clotting disorders or
• Congestive heart failure—This medicine should not be used.

• Kidney disease or
• Liver disease—Special caution should be used.

• Thrombocytopenia (low platelet count in the blood)—Caution should be used.

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