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Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Some side effects will have signs or symptoms that you can see or feel. Your doctor will watch for others by doing certain tests.
Also, because of the way tacrolimus acts on the body, there is a chance that it may cause effects that may not occur until years after the medicine is used. These delayed effects may include certain types of cancer, such as lymphomas or skin cancers.
Check with your doctor immediately if any of the following side effects occur:
More common- Abdominal pain
- Abnormal dreams
- Agitation
- Anxiety
- Chills
- Confusion
- Convulsions (seizures)
- Diarrhea
- Dizziness
- Fever and sore throat
- Flu-like symptoms
- Frequent urination
- Hallucinations (seeing or hearing things that are not there)
- Headache
- Infection
- Itching
- Loss of appetite
- Loss of energy or weakness
- Mental depression
- Muscle trembling or twitching
- Nausea
- Nervousness
- Pale skin
- Shortness of breath
- Skin rash
- Swelling of feet or lower legs
- Tingling
- Trembling and shaking of hands
- Trouble in sleeping
- Unusual bleeding or bruising
- Unusual tiredness or weakness
- Vomiting
- Blurred vision
- Chest pain
- Increased sensitivity to pain
- Muscle cramps
- Numbness or pain in legs
- Ringing in ears
- Sweating
- Enlarged heart
- Flushing of face or neck
- General feeling of discomfort or illness
- Weight loss
- Wheezing
- Black, tarry stools
- Blistering, peeling, loosening of skin
- Bloating
- Blood in urine
- Blurred vision
- Constipation
- Convulsions (seizures)
- Cough
- Cramping or burning
- Drowsiness
- Fainting
- Fast, slow, or irregular heartbeat
- Heartburn
- Increased blood pressure
- Increased thirst
- Indigestion
- Irregular heartbeat
- Itching
- Joint or muscle pain
- Lightheadedness
- Loss of appetite
- Lower back or side pain
- Nausea
- Pinpoint red spots on skin
- Pounding or rapid pulse
- Recurrent fainting
- Red, irritated eyes
- Red skin lesions, often with a purple center
- Shortness of breath
- Sores
- Stomach pain
- Sugar in the urine
- Troubled breathing
- Ulcers or white spots in mouth or on lips
- Weakness
- Weight gain
- Yellow eyes or skin
This medicine may also cause the following side effects that your doctor will watch for:
More common- Hyperkalemia (too much potassium in the blood)
- Hypomagnesemia (not enough magnesium in the blood)
- Kidney problems
- Hyperlipidemia (high cholesterol)
- Hypertension (high blood pressure)
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
