Cetuximab (Intravenous Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

• Blemishes on the skin or pimples
• Bloating or swelling of the face, arms, hands, lower legs, or feet
• Body aches or pain
• Chills
• Congestion
• Cough or hoarseness
• Deep cracks, grooves, or lines in the skin
• Difficult or labored breathing
• Dizziness
• Facial swelling
• Fever
• Headache
• Lower back or side pain
• Nausea
• Painful or difficult urination
• Pale skin
• Rapid weight gain
• Runny nose
• Severe dry skin
• Shortness of breath
• Skin rash
• Tender, swollen glands in the neck
• Tightness in the chest
• Tingling of the hands or feet
• Trouble with breathing on exertion
• Trouble with swallowing
• Unusual bleeding or bruising
• Unusual tiredness or weakness
• Unusual weight gain or loss
• Voice changes
• Vomiting
• Weakness
• Wheezing

• Anxiety
• Black, tarry stools
• Chest pain
• Confusion
• Decreased urination
• Dry mouth
• Fainting
• Fast heartbeat
• Increase in heart rate
• Lightheadedness
• Rapid, shallow breathing
• Sore throat
• Sores, ulcers, or white spots on the lips or in the mouth
• Sunken eyes
• Swollen glands
• Thirst
• Wrinkled skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Acid or sour stomach
• Belching
• Burning, dry, or itching eyes
• Diarrhea
• Difficulty having a bowel movement (stool)
• Discharge from the eye
• Discoloration of the fingernails or toenails
• Discouragement
• Excessive tearing
• Feeling sad or empty
• Hair loss or thinning of the hair
• Heartburn
• Indigestion
• Irritability
• Itching skin
• Lack or loss of appetite
• Lack or loss of strength
• Loss of interest or pleasure
• Pain
• Redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid
• Sleeplessness
• Stomach discomfort, upset, or pain
• Swelling or inflammation of the mouth
• Trouble concentrating
• Trouble sleeping
• Unable to sleep

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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