Exenatide (Subcutaneous Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Agitation
• Bloated or full feeling
• Chills
• Coma
• Confusion
• Constipation
• Cough
• Darkened urine
• Decreased urination or urine output
• Depression
• Difficulty with swallowing
• Dizziness
• Dry mouth
• Fainting
• Fast heartbeat
• Fever
• Headache
• Hives or welts
• Hostility
• Increase in heart rate
• Indigestion
• Irritability
• Itching skin
• Large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
• Lethargy
• Lightheadedness
• Loss of appetite
• Muscle twitching
• Nausea
• Pains in the stomach, side, or abdomen, possibly radiating to the back
• Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• Rapid breathing
• Rapid weight gain
• Seizures
• Shortness of breath
• Skin rash
• Stupor
• Sunken eyes
• Swelling of the face, ankles, or hands
• Thirst
• Tightness in the chest
• Unusual tiredness or weakness
• Vomiting
• Wheezing
• Wrinkled skin
• Yellow eyes or skin

Get emergency help immediately if any of the following symptoms of overdose occur:

• Anxiety
• Blurred vision
• Cold sweats
• Cool, pale skin
• Increased hunger
• Nervousness
• Nightmares
• Severe vomiting
• Shakiness
• Slurred speech

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Acid or sour stomach
• Belching
• Diarrhea
• Feeling jittery
• Heartburn
• Stomach discomfort or upset

• Appetite decreased
• Increased sweating
• Lack or loss of strength

• Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
• Change in taste
• Excess air or gas in the stomach or intestines
• Loss of taste
• Passing gas
• Pressure in the stomach
• Rash with flat lesions or small raised lesions on the skin
• Redness of the skin
• Sleepiness or unusual drowsiness
• Swelling of the abdomen or stomach area

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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