Proper Use
Take naltrexone regularly as ordered by your doctor. It may be helpful to have someone else, such as a family member, doctor, or nurse, give you each dose as scheduled.
Dosing
The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
- For oral dosage form (tablets):
- For narcotic addiction:
- Adults—25 milligrams (mg) (one-half tablet) for the first dose, then another 25 mg one hour later. After that, the dose is 350 mg a week. Your doctor will direct you to divide up this weekly dose and take naltrexone according to one of the following schedules:
- 50 mg (one tablet) every day; or
- 50 mg a day during the week and 100 mg (two tablets) on Saturday; or
- 100 mg every other day; or
- 100 mg on Mondays and Wednesdays, and 150 mg (three tablets) on Fridays; or
- 150 mg every three days.
- Children and teenagers up to 18 years of age—Use and dose must be determined by your doctor.
- Adults—25 milligrams (mg) (one-half tablet) for the first dose, then another 25 mg one hour later. After that, the dose is 350 mg a week. Your doctor will direct you to divide up this weekly dose and take naltrexone according to one of the following schedules:
- For alcoholism:
- Adults—The first dose may be 25 milligrams (mg) (one-half tablet). After that, the dose is 50 mg (one tablet) every day.
- Children and teenagers up to 18 years of age—Use and dose must be determined by your doctor.
- For narcotic addiction:
Missed Dose
Call your doctor or pharmacist for instructions.
Storage
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Ask your healthcare professional how you should dispose of any medicine you do not use.


Find Mayo Clinic on