Hepatitis B Vaccine (Intramuscular Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

• Fever of 37.7 degrees C (100 degrees F) or higher

• Aches or pain in the joints, fever, or skin rash or welts (may occur days or weeks after receiving the vaccine)
• Blurred vision or other vision changes
• Confusion
• Difficulty with breathing or swallowing
• Dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• Hives
• Itching, especially of the feet or hands
• Muscle weakness
• Numbness or tingling of the arms and legs
• Reddening of the skin, especially around the ears
• Sweating
• Swelling of the eyes, face, or inside of the nose
• Unusual tiredness or weakness (sudden and severe)

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Dizziness
• Headache
• Soreness at the injection site

• Hard lump, redness, swelling, pain, itching, purple spot, tenderness, or warmth at the injection site
• Unusual tiredness or weakness

• Aches or pain in the muscles
• Agitation
• Back pain or stiffness or pain in neck or shoulder
• Chills
• Constipation
• Diarrhea
• Difficulty with moving
• Feeling of warmth
• General feeling of discomfort or illness
• Headache (mild), sore throat, runny nose, or fever (mild)
• Increased sweating
• Itching
• Lack of appetite or decreased appetite
• Nausea or vomiting
• Redness of the face, neck, arms, and occasionally, upper chest
• Sleepiness or unusual drowsiness
• Sleeplessness
• Stomach cramps or pain
• Sudden redness of skin
• Swelling of glands in the armpit or neck
• Trouble with sleeping
• Unable to sleep
• Welts
• Weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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