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Before Using
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of celecoxib in children 2 years of age and older. However, safety and efficacy have not been established in children younger than 2 years of age.
Geriatric
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of celecoxib in the elderly. However, elderly patients are more likely to have age-related kidney or stomach problems, which may require caution and an adjustment in the dose for patients receiving celecoxib.
Pregnancy
| Pregnancy Category | Explanation |
|---|
Breastfeeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Drug Interactions
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Pemetrexed
- Warfarin
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Alacepril
- Aspirin
- Azosemide
- Bemetizide
- Benazepril
- Bendroflumethiazide
- Benzthiazide
- Bumetanide
- Buthiazide
- Candesartan Cilexetil
- Captopril
- Chlorothiazide
- Chlorthalidone
- Cilazapril
- Citalopram
- Clopamide
- Clovoxamine
- Cyclopenthiazide
- Cyclothiazide
- Delapril
- Desvenlafaxine
- Diltiazem
- Duloxetine
- Enalaprilat
- Enalapril Maleate
- Eprosartan
- Escitalopram
- Ethacrynic Acid
- Femoxetine
- Flesinoxan
- Fluconazole
- Fluoxetine
- Fluvoxamine
- Fosinopril
- Furosemide
- Hydrochlorothiazide
- Hydroflumethiazide
- Imidapril
- Indapamide
- Irbesartan
- Lisinopril
- Lithium
- Losartan
- Methyclothiazide
- Metolazone
- Milnacipran
- Moexipril
- Nefazodone
- Olmesartan Medoxomil
- Paroxetine
- Pentopril
- Perindopril
- Piretanide
- Polythiazide
- Quinapril
- Quinethazone
- Ramipril
- Sertraline
- Spirapril
- Tasosartan
- Telmisartan
- Temocapril
- Torsemide
- Trandolapril
- Trichlormethiazide
- Valsartan
- Venlafaxine
- Xipamide
- Zimeldine
- Zofenopril
Other Interactions
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
- Anemia or
- Edema (fluid retention or body swelling) or
- Heart attack, history of or
- Heart disease (e.g., congestive heart failure) or
- Hepatitis, history of or
- Hypertension (high blood pressure) or
- Kidney disease or
- Stomach ulcers or bleeding, history of or
- Stroke, history of—Use with caution. May make these conditions worse.
- Aspirin-sensitive asthma, history of or
- Aspirin sensitivity, history of or
- Sulfa or sulfonamide allergy—Should not be used in patients with these conditions.
- Heart surgery (e.g., coronary artery bypass graft [CABG] surgery)—This medicine should not be used to relieve pain right before or after the surgery.
- Liver disease—Use with caution. Effects may be increased because of slower removal of the medicine from the body.
