Celecoxib (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Cough
• Fever
• Skin rash
• Sneezing
• Sore throat
• Swelling of the face, fingers, feet, or lower legs

• Abnormal growth in the breast
• Arm, back, or jaw pain
• Bloody or black, tarry stools
• Blurred vision
• Burning feeling in the chest or stomach
• Burning or stinging of the skin
• Burning, tingling, numbness, or pain in the hands, arms, feet, or legs
• Chest pain or discomfort
• Chest tightness or heaviness
• Chills
• Confusion
• Congestion in the chest
• Cramps
• Diarrhea
• Dry mouth
• Earache
• Fast or irregular heartbeat
• Heartburn
• Heavy bleeding
• Heavy non-menstrual vaginal bleeding
• High blood pressure
• Increased hunger
• Increased thirst
• Increased urination
• Loss of appetite
• Loss of consciousness
• Muscle aches and pains
• Nausea
• Nerve pain
• Painful blisters on the trunk of body
• Painful cold sores or blisters on the lips, nose, eyes, or genitals
• Pale skin
• Redness or swelling in the ear
• Sensation of pins and needles
• Soreness or redness around the fingernails and toenails
• Stabbing pain
• Stiff neck
• Stomachache
• Stomach pain (severe)
• Sweating
• Tenderness in the stomach area
• Troubled breathing with exertion
• Unexplained weight loss
• Unusual bleeding or bruising
• Unusual tiredness or weakness
• Unusual weight gain
• Vomiting
• Vomiting of blood or material that looks like coffee grounds
• Weakness
• Wheezing

• Area rash
• Changes in skin color
• Clay-colored stools
• Dilated neck veins
• Light-colored stools
• Pale or a bluish color skin of the fingers or toes
• Seizures
• Slurred speech
• Sores, welting, or blisters
• Sudden and severe inability to speak
• Unpleasant breath odor
• Weakness in the arm or leg on one side of the body
• Yellow eyes and skin

Get emergency help immediately if any of the following symptoms of overdose occur:

• Continuing thirst
• Dizziness
• Drowsiness
• Headache, severe or continuing
• Shortness of breath
• Sudden decrease in the amount of urine
• Troubled breathing
• Weight gain

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Back pain
• Gas
• Headache
• Heartburn
• Inability to sleep
• Pain or burning in the throat
• Stuffy or runny nose

• Anxiety
• Bleeding after defecation
• Bloody or cloudy urine
• Breast pain
• Bone deformity
• Buzzing or ringing noise in the ears
• Change in sense of taste
• Constipation
• Decrease in height
• Decreased appetite
• Depression
• Difficult, burning, or painful urination
• Difficulty with moving or walking
• Difficulty with swallowing
• Excessive muscle tone, muscle tension, or tightness
• Excessive tearing
• Feeling of pressure
• Hair loss
• Hives
• Hoarseness
• Increased sweating
• Infection
• Inflammation
• Itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at site
• Itching of the vagina or genital area
• Joint or muscle pain or stiffness
• Large, flat, blue, or purplish patches in the skin
• Loss of energy or weakness
• Loss of hearing
• Muscle pain increased
• Muscle stiffness
• Nervousness
• Numbness or tingling in the fingers or toes
• Pain during sexual intercourse
• Pain in the back, ribs, arms, or legs
• Pounding heartbeat
• Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• Redness or swelling in the arms or legs
• Sensitivity of the skin to sunlight
• Severe sunburn
• Sleepiness
• Straining while passing stool
• Sudden sweating and feelings of warmth
• Swelling
• Swelling or inflammation of the mouth
• Tenderness
• Thick, white vaginal discharge with no odor or with a mild odor
• Thinning of the hair
• Trouble with swallowing
• Troubled breathing
• Uncomfortable swelling around anus
• Unexplained weight loss
• Voice changes
• Warmth on the skin
• Weakness or heaviness of the legs

• Bleeding gums
• Blistering, peeling, or loosening of the skin
• Bloating
• Large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
• Loss of sense of smell
• Pain
• Pinpoint red spots on the skin
• Red or irritated eyes
• Red skin lesions, often with a purple center
• Shakiness and unsteady walk
• Sores, ulcers, or white spots in the mouth or on the lips
• Stomach cramps
• Swelling of the neck
• Tenderness
• Trembling, or other problems with muscle control or coordination
• Unsteadiness
• Watery or bloody diarrhea

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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