Efavirenz, Emtricitabine, and Tenofovir (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Abdominal or stomach pain or tenderness
• Blistering, peeling, or loosening of the skin
• Body aches or pain
• Clay-colored stools
• Cough
• Dark urine
• Ear congestion
• Fever, chills
• Headache
• Itching
• Loss of voice
• Muscle aches
• Nausea and vomiting
• Severe skin rash
• Shortness of breath
• Sore throat
• Swelling of the feet or lower legs
• Tightness of the chest
• Trouble concentrating
• Yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Diarrhea
• Dizziness
• Unusual tiredness or weakness

• Abnormal dreams
• Decreased appetite
• Discouragement
• Feeling sad or empty
• Irritability
• Loss of appetite
• Loss of interest or pleasure
• Mild rash
• Pain or tenderness around the eyes and cheekbones
• Sleepiness
• Trouble sleeping
• Unusual drowsiness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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