Mayo Clinic Health Manager
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Follow carefully the special meal plan your doctor gave you. This is the most important part of controlling your condition, and is necessary if the medicine is to work properly. Also, exercise regularly and test for sugar in your blood or urine as directed.
This medicine should come with a medication guide. Read and follow these instructions carefully. Ask your doctor if you have any questions.
This medicine should be taken with the first meal of the day.
You may notice improvement in your blood glucose control in 1 to 2 weeks, but the full effect of blood glucose control may take up to 2 to 3 months. Ask your doctor if you have any questions about this.
Dosing
The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
- For type 2 diabetes:
- For oral dosage form (tablets):
- For patients already taking glimepiride alone:
- Adults—At first, 4 milligrams (mg) of rosiglitazone and 1 mg of glimepiride or 4 mg of rosiglitazone and 2 mg of glimepiride once a day, as directed by your doctor. Your doctor may gradually increase your dose until your blood sugar is controlled. However, the dose is usually not more than 8 mg of rosiglitazone and 4 mg of glimepiride.
- Children—Use and dose must be determined by your doctor.
- For patients already taking rosiglitazone alone:
- Adults—At first, 4 milligrams (mg) of rosiglitazone and 1 mg of glimepiride or 4 mg of rosiglitazone and 2 mg of glimepiride once a day, as directed by your doctor. Your doctor may gradually increase your dose until your blood sugar is controlled. However, the dose is usually not more than 8 mg of rosiglitazone and 4 mg of glimepiride.
- Children—Use and dose must be determined by your doctor.
- For patients switching from a combination of glimepiride and rosiglitazone as separate tablets:
- Adults—The dose is the same as the dose you are already taking. Your doctor may gradually increase your dose until your blood sugar is controlled. However, the dose is usually not more than 8 mg of rosiglitazone and 4 mg of glimepiride.
- Children—Use and dose must be determined by your doctor.
- For patients already taking glimepiride alone:
- For oral dosage form (tablets):
Missed Dose
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Storage
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Ask your healthcare professional how you should dispose of any medicine you do not use.