Ranolazine (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Dizziness

• Bloating or swelling of the face, arms, hands, lower legs, or feet
• Continuous ringing or buzzing or other unexplained noise in the ears
• Difficult or labored breathing
• Fast, irregular, pounding, or racing heartbeat or pulse
• Feeling of constant movement of self or surroundings
• Hearing loss
• Lightheadedness
• Rapid weight gain
• Sensation of spinning
• Shortness of breath
• Tightness in the chest
• Tingling of the hands or feet
• Unusual weight gain or loss
• Wheezing

• Abnormal or decreased touch sensation
• Blood in the urine
• Blurred vision
• Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
• Chest pain or discomfort
• Chills
• Cold sweats
• Confusion
• Dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• Fainting
• Shakiness in the legs, arms, hands, or feet
• Slow or irregular heartbeat
• Sweating
• Trembling or shaking of the hands or feet
• Unusual tiredness or weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Difficulty having a bowel movement (stool)
• Headache

• Dry mouth
• Stomach pain

• Lack or loss of strength

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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