Posaconazole (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Abdominal or stomach pain
• Black, tarry stools
• Bloody nose
• Blurred vision
• Body aches or pain
• Confusion
• Cough
• Diarrhea
• Difficult or labored breathing
• Dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• Drowsiness
• Fever or chills
• Fruit-like breath odor
• Heavy non-menstrual vaginal bleeding
• Increased thirst or urination
• Irregular heartbeats
• Loss of voice
• Muscle pain, spasms or twitching
• Nausea or vomiting
• Numbness or tingling in the hands, feet, lips, mouth, or fingertips
• Painful cold sores or blisters on the lips, nose, eyes, or genitals
• Painful or difficult urination
• Pounding in the ears
• Slow or fast heartbeat
• Small red or purple spots on the skin
• Sores, ulcers, or white spots on the lips, tongue, or inside the mouth
• Sweating
• Tender, swollen glands in the neck
• Tightness in the chest
• Trembling
• Trouble with swallowing
• Unexplained weight loss
• Yellow eyes or skin

• Fainting
• Irregular heartbeat, recurrent

• Anxiety
• Change in mental status
• Chest pain or discomfort
• Darkening of the skin
• Itching or skin rash
• Mental depression
• Seizures
• Sudden shortness of breath or troubled breathing
• Swelling of the eyes or eyelids
• Swelling of the face, fingers, feet, or lower legs
• Weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Acid or sour stomach
• Back pain
• Belching
• Difficulty having a bowel movement (stool)
• Heartburn
• Muscle stiffness
• Pain in the joints
• Trouble sleeping

• Bad, unusual, or unpleasant (after) taste
• Change in taste

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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