Panitumumab (Intravenous Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

• Abdominal or stomach pain
• Anxiety
• Bloating or swelling of the face, arms, hands, lower legs, ankles, or feet
• Chest pain
• Chills
• Confusion
• Constipation
• Convulsions
• Cough
• Decreased urination
• Deep cracks, grooves, or lines in the skin
• Diarrhea
• Difficulty with swallowing
• Discoloration of the fingernails or toenails
• Drowsiness
• Dry mouth, lips, or skin
• Fainting
• Fast or irregular heartbeat
• Fever
• Flushing or redness of the skin
• Increased thirst
• Itching, pain, and swelling of the eyelid
• Itching skin
• Loosening of the fingernails
• Loss of appetite
• Mood or mental changes
• Muscle pain or cramps
• Muscle spasms or twitching
• Nausea
• Rapid weight gain
• Rapid, shallow breathing
• Rash
• Redness or soreness around the fingernails
• Shortness of breath
• Sores, ulcers, or white spots on the lips, tongue, or inside the mouth
• Sudden shortness of breath
• Sunken eyes
• Swelling or inflammation of the mouth
• Tearing of the eyes
• Tingling of the hands or feet
• Trembling
• Troubled breathing
• Unusual tiredness or weakness
• Unusual weight gain or loss
• Unusually warm skin
• Vomiting

• Blurred vision
• Burning, dry, or itching eyes
• Difficulty with breathing
• Discharge from the eyes or excessive tearing
• Dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• Facial swelling
• Headache
• Hives
• Noisy breathing
• Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• Sweating
• Swelling of the eye, eyelid, or inner lining of the eyelid
• Tightness in the chest
• Wheezing

• Chest discomfort
• Painful breathing
• Slight fever
• Troubled or quick, shallow breathing

• Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, or warmth at the injection site
• Large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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