Corticosteroid (Rectal Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

• Burning and itching of skin
• Chills
• Depression
• Diarrhea
• False sense of well-being
• Fever
• Infection
• Mood swings
• Painful, red or itchy, pus-containing blisters in hair follicles
• Personality changes
• Rectal bleeding, burning, dryness, itching, or pain not present before therapy
• Sensation of pins and needles
• Stabbing pain
• Straining while passing stool (with tixocortol only)

Additional side effects may occur if you use this medicine for a long time. Check with your doctor as soon as possible if any of the following side effects occur:

• Abdominal or stomach pain
• Acne
• Backache
• Coughing
• Coughing up blood
• Decreased resistance to infection
• Dryness of mouth
• Eye pain
• Filling or rounding out of the face
• Gradual blurring or loss of vision
• Headache
• Hunchback
• Increased thirst
• Irregular heartbeat
• Loss of appetite
• Menstrual irregularities
• Mood or mental changes
• Muscle cramps or pain
• Muscle weakness
• Nausea or vomiting
• Nonelevated blue or purplish patch on the skin
• Osteoporosis or bone fractures
• Pain in joints
• Pain or discomfort in the area of a vein
• Rapid weight gain
• Reddish purple lines on arms, face, legs, trunk, or groin
• Redness of eye
• Sensitivity of eye to light
• Shortness of breath
• Skin rash
• Slow wound healing
• Stunting of growth (in children)
• Swelling of feet or lower legs
• Trouble in sleeping
• Unusual decrease in sexual desire or ability in men
• Tearing of eyes
• Unusual increase in hair growth (especially on the face)
• Unusual tiredness or weakness
• Unusual weight loss
• Weak pulse

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Dizziness
• Dry, scaly skin
• Increase in appetite
• Increased sweating
• Lightened skin color
• Passing of gas (with budesonide only)
• Sensation of spinning
• Thin, fragile skin
• Thinning hair on scalp
• Unusual weight gain

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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