Decitabine (Intravenous Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common
  • Black, tarry stools
  • Bladder pain
  • Bleeding after defecation
  • Bleeding gums
  • Blood in urine or stools
  • Bloody or cloudy urine
  • Blue lips and fingernails
  • Blurred vision
  • Body aches or pain
  • Chest pain
  • Chills
  • Coma
  • Congestion
  • Convulsions
  • Cough
  • Coughing that sometimes produces a pink frothy sputum
  • Decreased urination
  • Difficult, burning, or painful urination
  • Difficult, fast, noisy breathing, sometimes with wheezing
  • Dizziness, faintness, or lightheadedness when getting up from a lying or sitting position
  • Drowsiness
  • Dry mouth
  • Dryness of throat
  • Facial swelling
  • Fainting
  • Fast or irregular heartbeat
  • Feeling unusually cold
  • Fever
  • Flushed, dry skin
  • Frequent urge to urinate
  • Fruit-like breath odor
  • Headache
  • Hives or welts
  • Hoarseness
  • Increased hunger
  • Increased sweating
  • Increased thirst
  • Increased urination
  • Itching, pain, redness, swelling, tenderness, or warmth on skin
  • Lightheadedness
  • Loss of appetite
  • Lower back or side pain
  • Mood or mental changes
  • Muscle pain or cramps
  • Muscle spasms or twitching
  • Nausea or vomiting
  • Nervousness
  • Numbness or tingling in hands, feet, or lips
  • Pale skin
  • Pinpoint red spots on skin
  • Redness or pain at the catheter site
  • Runny nose
  • Seizures
  • Shivering
  • Shortness of breath
  • Skin rash
  • Small clicking, bubbling, or rattling sounds in the lung when listening with a stethoscope
  • Small red or purple spots on skin, lips or in mouth
  • Sneezing
  • Sore mouth or tongue
  • Sore throat
  • Sores, ulcers, or white spots on lips or in mouth
  • Stomach pain and bloating
  • Sunken eyes
  • Swelling of face, hands, ankles, feet, or lower legs
  • Swollen, painful, or tender lymph glands in neck, armpit, or groin
  • Tightness in chest
  • Trembling
  • Trouble in swallowing
  • Troubled breathing with exertion
  • Uncomfortable swelling around anus
  • Unexplained weight loss
  • Unusual bleeding or bruising
  • Unusual tiredness or weakness
  • Voice changes
  • Weakness or heaviness of legs
  • Wheezing
  • White patches in mouth and/or on tongue
  • Wrinkled skin
  • Yellow eyes or skin
Less common
  • Collection of blood under skin
  • Deep, dark purple bruise
  • Diarrhea
  • Pain or tenderness around eyes and cheekbones
  • Pain, warmth, or burning in fingers, toes, and legs
  • Problems with vision or hearing
  • Skin scrape or burn
  • Stuffy nose
  • Swelling at injection site

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Acid or sour stomach
  • Anxiety
  • Back pain
  • Belching
  • Bumps on skin
  • Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • Chest discomfort
  • Constipation
  • Difficulty swallowing
  • Fall
  • Hair loss, thinning of hair
  • Heartburn
  • Indigestion
  • Loose stools
  • Muscle stiffness
  • Pain in arms or legs
  • Pain in joints
  • Sleeplessness
  • Stomach discomfort or upset
  • Swelling or inflammation of the mouth
  • Trouble sleeping
  • Unable to sleep
  • Unusual drowsiness, dullness, or feeling of sluggishness
Less common
  • Difficulty in moving
  • General feeling of discomfort or illness
  • Muscle aching
  • Pain in the tongue
  • Postnasal drip
  • Pressure in the stomach
  • Swollen joints

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Precautions
DR602349 Portions of this document last updated: Nov. 1, 2011

Source: Drug Information provided by: Micromedex

Copyright © 2013 Thomson Healthcare Inc. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.

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