Paliperidone (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Difficulty with speaking
• Drooling
• Fast, pounding, or irregular heartbeat or pulse
• Increase in body movements
• Loss of balance control
• Muscle trembling, jerking, or stiffness
• Restlessness
• Shuffling walk
• Stiffness of the limbs
• Twisting movements of the body
• Uncontrolled movements, especially of the face, neck, and back

• Chest pain
• Cold sweats
• Confusion
• Cough
• Difficulty with swallowing
• Dizziness
• Excessive muscle tone
• Fainting
• Inability to move the eyes
• Increased blinking or spasms of the eyelid
• Increased blood pressure
• Loss of balance control
• Mask-like face
• Muscle tension or tightness
• Pain in the arms or legs
• Slow heartbeat
• Slowed movements
• Slurred speech
• Sticking out tongue when not meaning to
• Tic-like (jerky) movements of the head, face, mouth, and neck
• Trembling and shaking of the fingers and hands
• Tremors
• Trouble with breathing, speaking, or swallowing
• Uncontrolled twisting movements of the neck, trunk, arms, or legs
• Unusual facial expressions
• Unusual tiredness or weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Absent, missed, or irregular menstrual periods
• Difficulty having a bowel movement (stool)
• Fear or nervousness
• Headache
• Inability to sit still
• Nausea
• Need to keep moving
• Sleepiness or unusual drowsiness
• Stopping of menstrual bleeding
• Vomiting
• Weight gain

• Acid or sour stomach
• Back pain
• Belching
• Blurred vision
• Changes in appetite
• Dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• Dry mouth
• Fever
• Heartburn
• Indigestion
• Lack or loss of strength
• Muscle aches
• Sore throat
• Stomach discomfort, upset, or pain
• Stuffy or runny nose
• Swelling of the breasts or breast soreness in both females and males
• Swollen tongue
• Unexpected or excess milk flow from breasts
• Upper abdominal or stomach pain

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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