Nelarabine (Intravenous Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Abdominal pain or cramps
• Anxiety
• Black, tarry stools
• Bleeding gums
• Blood in the urine or stools
• Bloody nose
• Blurred vision
• Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
• Change in walking and balance
• Chest pain
• Chills
• Clumsiness or unsteadiness
• Cold sweats
• Coma
• Convulsions
• Cool, pale skin
• Cough or hoarseness
• Decreased or uncontrolled urination
• Difficulty with breathing
• Discouragement
• Dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
• Drowsiness
• Dry mouth
• Fast or irregular heartbeat
• Feeling sad or empty
• Feeling unusually cold
• Fever
• Flushed, dry skin
• Fruit-like breath odor
• Headache
• Incoordination
• Increased hunger
• Increased thirst
• Increased urination
• Irritability
• Loss of appetite
• Loss of interest or pleasure
• Lower back, side, or stomach pain
• Mood or mental changes
• Muscle cramps in hands, arms, feet, legs, or face
• Muscle pain
• Muscle spasms (tetany) or twitching seizures
• Muscle weakness
• Nausea or vomiting
• Nervousness
• Nightmares
• Numbness, tingling, pain, or weakness in hands, feet, fingertips, or mouth
• Pain or tenderness around the eyes and cheekbones
• Painful or difficult urination
• Paralysis or severe weakness of legs
• Rapid breathing
• Seizures
• Shakiness and unsteady walk
• Shivering
• Shortness of breath
• Sleepiness or unusual drowsiness
• Sleeplessness
• Slurred speech
• Small red or purple spots on skin
• Sneezing
• Sore throat
• Sores, ulcers, or white spots on the lips or in the mouth
• Stuffy or runny nose
• Sunken eyes
• Sweating
• Swelling of hands, ankles, feet, or lower legs
• Swollen glands
• Tightness in chest
• Trouble concentrating
• Trouble sleeping
• Troubled breathing with exertion
• Unable to sleep
• Uncontrolled bowel movements
• Unexplained weight loss
• Unsteadiness, trembling, or other problems with muscle control or coordination
• Unusual bleeding or bruising
• Unusual tiredness or weakness
• Wheezing
• Wrinkled skin
• Yellow eyes or skin

• Change in taste
• Loss of memory
• Loss of taste
• Problems with memory

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Back pain
• Diarrhea
• Difficulty having a bowel movement (stool)
• Difficulty with moving
• Full or bloated feeling
• Joint pain
• Lack or loss of strength
• Muscle aching or stiffness
• Pain in the arms or legs
• Pressure in the stomach
• Swelling of the abdomen or stomach area
• Swelling or inflammation of the mouth
• Swollen joints

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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