Lisdexamfetamine Dimesylate (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Uncontrolled vocal outbursts and/or tics (uncontrolled repeated body movements)

• Blistering, peeling, or loosening of the skin
• Chest discomfort or pain
• Chills
• Cough
• Diarrhea
• Difficulty with breathing
• Difficulty with swallowing
• Discouragement
• Dizziness
• Faintness
• Fast, irregular, pounding, or racing heartbeat or pulse
• Feeling sad or empty
• Hives or welts
• Irritability
• Itching
• Joint or muscle pain
• Lack of appetite
• Large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
• Loss of interest or pleasure
• Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• Red skin lesions, often with a purple center
• Red, irritated eyes
• Redness of the skin
• Shortness of breath
• Skin rash
• Sore throat
• Sores, ulcers, or white spots in the mouth or on the lips
• Swelling of the feet or lower legs
• Tightness in the chest
• Trouble concentrating
• Trouble sleeping
• Troubled breathing
• Twitching, twisting, or uncontrolled repetitive movements of the tongue, lips, face, arms, or legs
• Unusual tiredness or weakness
• Wheezing

Get emergency help immediately if any of the following symptoms of overdose occur:

• Abdominal or stomach cramps
• Blurred vision
• Change in consciousness
• Confusion
• Dark-colored urine
• Dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• Fast breathing
• Loss of consciousness
• Muscle cramps or spasms
• Muscle pain or stiffness
• Nervousness
• Overactive reflexes
• Panic states
• Physical attempt to injure yourself
• Pounding in the ears
• Restlessness
• Seeing, hearing, or feeling things that are not there
• Seizures
• Shakiness in the legs, arms, hands, or feet
• Sweating
• Trembling or shaking of the hands or feet
• Violent actions

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Decreased appetite
• Headache
• Nausea
• Sleeplessness
• Unable to sleep
• Upper abdominal or stomach pain
• Vomiting
• Weight decreased

• Crying
• Depersonalization
• Dry mouth
• Dysphoria
• Euphoria
• Fever
• Paranoia
• Quick to react or overreact emotionally
• Rapidly changing moods
• Rash
• Sleepiness or unusual drowsiness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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