Lapatinib (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Difficult or labored breathing
• Fainting
• Fast or irregular heartbeat
• Severe diarrhea
• Shortness of breath
• Tightness in the chest
• Unusual tiredness or weakness
• Wheezing

• Chest pain
• Chills
• Cough
• Fever
• General feeling of discomfort or illness
• Thickening of bronchial secretions
• Troubled breathing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Acid or sour stomach
• Back pain
• Belching
• Cracked lips
• Diarrhea
• Difficulty with swallowing
• Dry skin
• Heartburn
• Indigestion
• Nausea
• Pain in the arms or legs
• Rash
• Redness, swelling, or painful skin
• Scaling of the skin on the hands and feet
• Sleeplessness
• Sores, ulcers, or white spots on the lips, tongue, or the inside of the mouth
• Stomach discomfort, upset, or pain
• Swelling or inflammation of the mouth
• Tingling of the hands and feet
• Trouble sleeping
• Unable to sleep
• Vomiting

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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