Eculizumab (Intravenous Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

• Back pain
• Black, tarry stools
• Bladder pain
• Bloody or cloudy urine
• Blurred vision
• Burning or stinging of the skin
• Chest pain
• Cough
• Difficult, burning, or painful urination
• Difficulty with moving
• Dizziness
• Fever
• Headache
• Joint pain
• Lower back or side pain
• Muscle aching or cramping
• Muscle pains or stiffness
• Nausea
• Nervousness
• Pain or tenderness around the eyes and cheekbones
• Painful cold sores or blisters on the lips, nose, eyes, or genitals
• Pale skin
• Pounding in the ears
• Shortness of breath or troubled breathing
• Slow or fast heartbeat
• Sneezing
• Sore throat
• Sores, ulcers, or white spots on lips or in the mouth
• Stuffy or runny nose
• Swollen glands
• Swollen joints
• Tightness of the chest or wheezing
• Troubled breathing with exertion
• Unusual bleeding or bruising
• Unusual tiredness or weakness

• Chills
• Diarrhea
• General feeling of discomfort or illness
• Loss of appetite
• Shivering
• Sweating
• Trouble sleeping
• Vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Difficulty having a bowel movement (stool)
• Pain in the arms or legs

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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