Nadolol and Bendroflumethiazide (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Blurred vision
• Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
• Chest pain or discomfort
• Confusion
• Cough
• Difficulty breathing
• Dilated neck veins
• Dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
• Extreme fatigue
• Irregular breathing
• Lightheadedness, dizziness, or fainting
• Noisy breathing
• Paleness or cold feeling in fingertips and toes
• Shortness of breath
• Slow or irregular heartbeat
• Slurred speech
• Sweating
• Swelling of face, fingers, feet, or lower legs
• Tightness in chest
• Tingling or pain in fingers or toes when exposed to cold
• Unusual tiredness or weakness
• Weight gain
• Wheezing

• Back or leg pains
• Black, tarry stools
• Bleeding gums
• Bloating
• Blood in urine or stools
• Chills
• Clay-colored stools
• Cloudy urine
• Cold sweats
• Constipation
• Coughing up blood
• Dark urine
• Difficulty swallowing
• Drowsiness
• Dry mouth
• Fast heartbeat
• Fever
• Flushed, dry skin
• Fruit-like breath odor
• General body swelling
• General feeling of discomfort or illness
• General tiredness and weakness
• Headache
• Hives
• Hoarseness
• Increased hunger
• Increased thirst
• Increased urination
• Indigestion
• Joint pain, stiffness, or swelling
• Light-colored stools
• Loss of appetite
• Lower back or side pain
• Muscle tremors
• Nausea and vomiting
• Nosebleeds
• Pain in muscles
• Painful or difficult urination
• Pains in stomach, side, or abdomen, possibly radiating to the back
• Pale skin
• Pinpoint red spots on skin
• Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• Rapid, deep breathing
• Rash
• Redness, soreness, or itching skin
• Restlessness
• Skin rash
• Sore throat
• Sores, ulcers, or white spots on lips or in mouth
• Sores, welting or blisters
• Stomach cramps
• Sugar in the urine
• Swollen or painful glands
• Tenderness of salivary glands
• Thickening of bronchial secretions
• Troubled breathing
• Unpleasant breath odor
• Unusual bleeding or bruising
• Unusual weight loss
• Upper right abdominal pain
• Vomiting of blood
• Yellow eyes or skin

Get emergency help immediately if any of the following symptoms of overdose occur:

• Change in consciousness
• Decreased urination
• Diarrhea
• Fast, slow, or shallow breathing
• Gas
• Heartburn
• Increase in heart rate
• Increased sweating
• Indigestion
• Loss of consciousness
• Low blood pressure
• Muscle cramps
• Numbness, tingling, pain, or weakness in hands or feet
• Pale or blue lips, fingernails, or skin
• Seizures
• Sunken eyes
• Trembling
• Unusual drowsiness, dullness, or feeling of sluggishness
• Unusual paleness
• Weakness and heaviness of legs
• Wrinkled skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Change in behavior
• Continuing ringing or buzzing or other unexplained noise in ears
• Decreased interest in sexual intercourse
• Dry eyes or skin
• Excess air or gas in stomach or intestines
• Hair loss, thinning of hair
• Hearing loss
• Inability to have or keep an erection
• Loss in sexual ability, desire, drive, or performance
• Relaxed and calm
• Sleepiness
• Stomach soreness or discomfort
• Stuffy nose
• Weight loss

• Cracks in the skin
• Discoloration of skin
• Feeling of constant movement of self or surroundings
• Increased sensitivity of skin to sunlight
• Large, flat, blue or purplish patches in the skin
• Loss of heat from the body
• Muscle spasm, weakness, or restlessness
• Scaly skin
• Sensation of spinning
• Severe sunburn

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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