Metoprolol and Hydrochlorothiazide (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common
  • Chest pain or discomfort
  • Convulsions
  • Decreased urine
  • Dry mouth
  • Increased thirst
  • Lightheadedness, dizziness, or fainting
  • Loss of appetite
  • Mood changes
  • Muscle pain or cramps
  • Nausea or vomiting
  • Numbness or tingling in the hands, feet, or lips
  • Shortness of breath
  • Slow or irregular heartbeat
  • Unusual tiredness or weakness
Less common
  • Ankle, knee, or great toe joint pain
  • Decreased ability to exercise
  • Difficult or labored breathing
  • Joint stiffness or swelling
  • Lower back or side pain
  • Swelling of the face, fingers, feet, or lower legs
  • Tightness in the chest
  • Wheezing

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose
  • Blurred vision
  • Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • Chemical imbalance in the blood
  • Cold, clammy skin
  • Coma
  • Confusion
  • Cough
  • Difficulty with breathing
  • Dilated neck veins
  • Dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • Drowsiness
  • Extreme fatigue
  • Fast or pounding heartbeat or pulse
  • Frequent urination
  • Headache
  • Increased volume of pale, dilute urine
  • Irregular breathing
  • Irritability
  • Mood changes
  • Noisy breathing
  • Not able to pass urine
  • Pain or aching in the lower legs
  • Pain or weakness in the hands or feet
  • Seizures
  • Sweating
  • Trembling
  • Unconsciousness
  • Very drowsy or sleepy
  • Weak pulse
  • Weakness and heaviness of the legs
  • Weight gain

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Chills
  • Diarrhea
  • Feeling of constant movement of self or surroundings
  • Fever
  • General feeling of discomfort or illness
  • Muscle aches
  • Nightmares
  • Runny nose
  • Sensation of spinning
  • Shivering
  • Sleepiness
  • Sore throat
  • Trouble sleeping
  • Unusual drowsiness, dullness, or feeling of sluggishness
Less common
  • Continuing ringing or buzzing or other unexplained noise in the ears
  • Decreased interest in sexual intercourse
  • Difficulty having a bowel movement (stool)
  • Earache
  • Hearing loss
  • Inability to have or keep an erection
  • Loss in sexual ability, desire, drive, or performance
  • Pinpoint red or purple spots on the skin
  • Weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Precautions
DR602509 Portions of this document last updated: Aug. 1, 2012

Source: Drug Information provided by: Micromedex

Copyright © 2013 Thomson Healthcare Inc. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.

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