Doripenem (Intravenous Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

• Bluish color
• Changes in skin color
• Diarrhea
• Pain, tenderness, or swelling of the foot or leg
• Pale skin
• Troubled breathing with exertion
• Unusual bleeding or bruising
• Unusual tiredness or weakness

• Bloody urine
• Decreased frequency or amount of urine
• Increased blood pressure
• Increased thirst
• Itching or pain of the vagina or genital area
• Loss of appetite
• Lower back or side pain
• Nausea
• Sore mouth or tongue
• Swelling of the face, fingers, or lower legs
• Thick, white vaginal discharge with mild or no odor
• Troubled breathing
• Vomiting
• Weight gain
• White patches in mouth or on tongue

• Blistering, peeling, or loosening of skin
• Chills
• Cough
• Difficulty with breathing
• Difficulty with swallowing
• Dizziness
• Fast heartbeat
• Fever
• Hives
• Itching
• Joint or muscle pain
• Loss of bladder control
• Muscle spasm or jerking of all extremities
• Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• Red skin lesions, often with a purple center
• Red, irritated eyes
• Shortness of breath
• Skin rash
• Sore throat
• Sores, ulcers, or white spots in the mouth or on lips
• Sudden loss of consciousness
• Tightness in chest
• Total body jerking
• Wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Headache

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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