Olanzapine (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Bloating or swelling of the face, arms, hands, lower legs, or feet
• Blurred vision
• Change in vision
• Change in walking and balance
• Clumsiness or unsteadiness
• Difficulty with speaking
• Difficulty with swallowing
• Drooling
• Impaired vision
• Inability to sit still
• Loss of balance control
• Mask-like face
• Muscle trembling, jerking, or stiffness
• Need to keep moving
• Rapid weight gain
• Restlessness
• Shakiness in the legs, arms, hands, or feet
• Shuffling walk
• Slowed movements
• Slurred speech
• Stiffness of the arms and legs
• Tic-like (jerky) movements of the head, face, mouth, and neck
• Tingling of the hands or feet
• Trembling or shaking of the fingers, hands, or feet
• Twisting movements of the body
• Uncontrolled movements, especially of the face, neck, and back
• Unusual weight gain or loss

• Bladder pain
• Bloody or cloudy urine
• Bruising
• Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
• Chest pain
• Difficult or labored breathing
• Difficult, burning, or painful urination
• Dizziness
• Excessive muscle tone
• Frequent urge to urinate
• Headache
• Inability to move the eyes
• Increased blinking or spasms of the eyelid
• Itching of the vagina or genital area
• Lack of coordination
• Large, flat, blue, or purplish patches in the skin
• Loss of bladder control
• Loss of memory
• Lower back or side pain
• Muscle tension or tightness
• Nervousness
• Pain during sexual intercourse
• Pounding in the ears
• Problems with memory
• Rhythmic movement of the muscles
• Shortness of breath
• Slow, fast, pounding, or irregular heartbeat or pulse
• Speaking is less clear than usual
• Sticking out the tongue
• Thick, white vaginal discharge with no odor or with a mild odor
• Tightness in the chest
• Trouble with breathing, speaking, or swallowing
• Twitching
• Uncontrolled twisting movements of the neck, trunk, arms, or legs
• Unusual or incomplete body or facial movements
• Weakness of the arms and legs
• Wheezing

Get emergency help immediately if any of the following symptoms of overdose occur:

• Anxiety
• Attacking, assaulting, or using force
• Change in consciousness
• Change in patterns and rhythms of speech
• Confusion as to time, place, or person
• Convulsions (seizures)
• Dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
• Drowsiness
• Dry mouth
• Fainting
• Hallucinations
• Heart stops beating
• High fever
• High or low blood pressure
• Holding false beliefs that cannot be changed by fact
• Increased sweating
• Irregular, fast or slow, or shallow breathing
• Irritability
• Lightheadedness
• Loss of consciousness
• Mood or mental changes
• No breathing
• No pulse or blood pressure
• Pale or blue lips, fingernails, or skin
• Rapid breathing
• Relaxed and calm
• Severe muscle stiffness
• Shaking or trembling
• Sleepiness
• Trouble with sleeping
• Unconscious
• Unusual excitement, nervousness, or restlessness
• Unusual tiredness or weakness
• Unusually pale skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Acid or sour stomach
• Back pain
• Belching
• Change in personality
• Difficulty having a bowel movement (stool)
• Discouragement
• Feeling sad or empty
• Fever
• Heartburn
• Increased appetite
• Increased cough
• Indigestion
• Lack of appetite
• Lack or loss of strength
• Loss of interest or pleasure
• Runny nose
• Sleeplessness
• Sneezing
• Stomach discomfort, upset, or pain
• Stuffy nose
• Thirst
• Trouble with concentrating
• Unable to sleep
• Watering of the mouth
• Weight gain

• Blemishes on the skin
• Body aches or pain
• Chills
• Cold sweats
• Congestion
• Cough
• Dry skin
• Dryness or soreness of the throat
• False or unusual sense of well-being
• Joint pain
• Heavy menstrual bleeding (periods)
• Hoarseness
• Lack of feeling or emotion
• Leg cramps
• Pain in the arms or legs
• Pimples
• Sweating
• Tender, swollen glands in the neck
• Uncaring feelings
• Voice change
• Vomiting

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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