It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly. Blood tests may be needed to check for unwanted effects .
Ketoconazole should not be taken with astemizole (e.g., Hismanal), cisapride (e.g., Propulsid), or terfenadine (e.g., Seldane). Doing so may increase the risk of serious side effects that affect the heart .
Liver problems may occur while you are taking this medicine. Check with your doctor right away if you are having more than one of these symptoms: abdominal pain or tenderness; clay-colored stools; dark urine; decreased appetite; fever; headache; itching; loss of appetite; nausea and vomiting; skin rash; swelling of the feet or lower legs; unusual tiredness or weakness; or yellow eyes or skin .
If your symptoms do not improve, or if they become worse, check with your doctor. You may need to take this medicine for several months before your infection gets better .