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Precautions
It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly and to check for unwanted effects.
If your symptoms do not improve, or if they become worse, check with your doctor. You may need to take this medicine for several weeks or months before your infection gets better.
Stop using this medicine and check with your doctor right away if you are having chest pain; decreased urine output; dilated neck veins; extreme fatigue; irregular breathing; an irregular heartbeat; shortness of breath; swelling of the face, fingers, feet, or lower legs; tightness in the chest; troubled breathing; weight gain; or wheezing. These could be symptoms of a side effect called congestive heart failure.
Itraconazole should not be taken with cisapride (Propulsid®), dofetilide (Tikosyn™), oral midazolam (Versed®), nisoldipine (Sular®), pimozide (Orap®), quinidine (Quinaglute®), triazolam (Halcion®), or levomethadyl (Orlaam®). You should not use itraconazole if you are also using lovastatin (Mevacor®), simvastatin (Zocor®), or an ergot medicine such as dihydroergotamine (Migranal®), ergometrine or ergonovine (Ergotrate Maleate®), ergotamine (Ergomar®), or methylergometrine or methylergonovine (Methergine®). Doing so may increase the risk of serious side effects.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.
Make sure your doctor knows if you are pregnant or planning to get pregnant before you start using this medicine for a fingernail or toenail infection. The oral capsule should not be used to treat onychomycosis in pregnant women or those who are planning to get pregnant. Use an effective form of birth control while you are using this medicine and for 2 months after you stop using it. If you think you have become pregnant while using the medicine, tell your doctor right away.
Liver problems may occur while you are taking this medicine. Check with your doctor right away if you are having more than one of these symptoms: stomach pain or tenderness; clay-colored stools; dark urine; decreased appetite; fever; headache; itching; loss of appetite; nausea and vomiting; skin rash; swelling of the feet or lower legs; unusual tiredness or weakness; or yellow eyes or skin.
Stop using this medicine and call your doctor right away if your skin feels like it is burning, crawling, itching, or if you have numbness, prickling, "pins and needles", or a tingling feeling after taking itraconazole.
Temporary or permanent hearing loss may occur while you are taking this medicine. Stop using this medicine and check with your doctor right away if you have any changes in your hearing.
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