Oxymorphone (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Blurred vision
• Confusion
• Decreased urination
• Difficult or labored breathing
• Dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• Dry mouth
• Fast, pounding, racing, or irregular heartbeat or pulse
• Headache
• Nervousness
• Pounding in the ears
• Rapid breathing
• Shortness of breath
• Sunken eyes
• Sweating
• Swelling of the hands, ankles, or feet
• Thirst
• Tightness in the chest
• Unusual tiredness or weakness
• Wheezing
• Wrinkled skin

• Abdominal or stomach pain
• Chest pain or discomfort
• Chills
• Cold sweats
• Cough
• Decrease in consciousness
• Decrease in urine volume
• Difficulty in passing urine (dribbling)
• Difficulty with sleeping
• Difficulty with swallowing
• Disorientation
• Drowsiness to profound coma
• Fear
• Fever
• Hallucination
• Hives
• Hyperventilation
• Hoarseness
• Irregular, slow, or shallow breathing
• Irritability
• Irritation
• Itching
• Joint pain, stiffness, or swelling
• Lethargy
• Mood or other mental changes
• Painful urination
• Pale or blue lips, fingernails, or skin
• Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• Redness of the skin
• Restlessness
• Severe constipation
• Severe vomiting
• Shaking
• Shortness of breath
• Skin rash
• Swelling of the eyelids, face, or lips
• Trouble in holding or releasing urine
• Trouble with sleeping
• Troubled breathing or swallowing

Get emergency help immediately if any of the following symptoms of overdose occur:

• Cold and clammy skin
• Constricted, pinpoint, or small pupils (black part of the eye)
• Decreased awareness or responsiveness
• Muscle weakness
• No blood pressure or pulse
• Not breathing
• Severe sleepiness or unusual drowsiness
• Stopping of heart

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Difficulty having a bowel movement (stool)
• Feeling of constant movement of self or surroundings
• Increased sweating
• Nausea or vomiting
• Relaxed and calm
• Sensation of spinning
• Sleepiness

• Acid or sour stomach
• Belching
• Decreased appetite
• Decreased weight
• Diarrhea
• Discouragement
• Excess air or gas in the stomach or intestines
• Feeling of warmth
• Feeling sad or empty
• Full or bloated feeling
• Heartburn
• Indigestion
• Lack of appetite
• Loss of interest or pleasure
• Passing gas
• Pressure in the stomach
• Redness of the face, neck, arms, and occasionally, upper chest
• Sleeplessness
• Stomach discomfort or upset
• Swelling of the abdominal or stomach area
• Tiredness
• Trouble concentrating
• Unable to sleep

• Blistering, crusting, irritation, itching, or reddening of the skin
• Cracked, dry, scaly skin
• Difficulty with thinking or concentrating
• Disturbed color perception
• Double vision
• False or unusual sense of well-being
• Feeling jittery
• Halos around lights
• Loss of vision
• Mental depression
• Night blindness
• Nightmares or unusually vivid dreams
• Overbright appearance of lights
• Sudden sweating
• Tunnel vision
• Welts

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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